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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
renal vascular resistance
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "renal vascular resistance" in MCE Product Catalog:
Target:
Research Areas:
IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo .
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Cat. No.: HY-P1615
CAS No.: 1006388-38-0
Synonyms: UPARANT
Cat. No.: HY-P0083A
CAS No.: 914453-98-8
Synonyms: POR-8 acetate
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Cat. No.: HY-W153159
CAS No.: 13062-76-5
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Target:
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Guancydine (Guancidine) is an orally active antihypertensive agent and vasodilator. Guancydine antagonizes the pressor effects of Angiotensin and Norepinephrine (HY-13715). Guancydine induces vasodilation in renal, mesenteric and cranial vascular beds, reduces peripheral resistance, increases cardiac output and lowers arterial blood pressure. Guancydine increases renal and forearm blood flow, reduces renal and forearm vascular resistance, alters cardiac systolic time, and reverses myocardial hypertrophy in hypertensive rats. Guancydine is applicable for research related to hypertension .
Cat. No.: HY-W153897
CAS No.: 370-98-9
Category:
Alkaloids Human Gut Microbiota Metabolites Leguminosae Other Alkaloids Acacia auriculiformis A.Cunn. ex Benth Plants Endogenous metabolite
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Cat. No.: HY-106837
CAS No.: 117279-73-9
Synonyms: Y 24180
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Israpafant (Y-24180) is a potent, selective and long-acting platelet activation factor (PAF) receptor antagonist with IC50s of 0.84 nM and 3.84 nM against PAF-induced human and rabbit platelet aggregation, respectively. Israpafant stimulates both extracellular Ca 2+ influx and intracellular Ca 2+ release in prostate cancer cells. Israpafant suppresses the allergic cutaneous reactions including eosinophilia, cytokine production, edema and erythema in mice .
Cat. No.: HY-127026S
CAS No.: 1279034-23-9
Cat. No.: HY-W153897R
CAS No.: 370-98-9
Cat. No.: HY-103460R
CAS No.: 169545-27-1
Research Areas:
IRL 2500 (Standard) is the analytical standard of IRL 2500 (HY-103460). This product is intended for research and analytical applications. IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo .
Cat. No.: HY-118229
CAS No.: 120442-40-2
Synonyms: DPMA; PD 125944
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CGS 24012 (DPMA) is a selective adenosine A2 agonist. CGS 24012 produces significant increases in cardiac output. CGS 24012 reduces renal vascular resistance to the greatest extent and produces a concomitant significant increase in renal blood flow. CGS 24012 can be used in the research of hypertension .
Cat. No.: HY-W153159R
CAS No.: 13062-76-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
