IRL 2500 (Standard)
IRL 2500 (Standard) is the analytical standard of IRL 2500 (HY-103460). This product is intended for research and analytical applications. IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 169545-27-1
- Fòrmula: C36H35N3O4
- Peso molecular:573.68
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
-
HY-103460
IRL 2500ETB Antagonist -
HY-102029
Sarafotoxin S6cEndothelin-B Receptor Agonist -
HY-A0013
BosentanET-1 Inhibtior -
HY-P0202
Endothelin 1 (swine, human)Vasoconstrictor -
HY-11103
Sitaxsentan sodiumEndothelin A Receptor Antagonist -
HY-15403A
Atrasentan hydrochlorideETA Receptor Antagonist -
HY-17351
TezosentanET Receptor Antagonist -
HY-13209
Ambrisentan -
HY-16465
IRL-1620ETB Agonist -
HY-15894A
BQ-788ETB Receptor Antagonist -
HY-12378
BQ-123ETA Receptor Antagonist -
HY-14184
MacitentanETA/ETB Antagonist
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
No. CAS 169545-27-1
-
Peso molecular 573.68
-
Fòrmula C36H35N3O4
-
SMILES
O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC([C@@H](CC3=CC=C(C4=CC=CC=C4)C=C3)N(C(C5=CC(C)=CC(C)=C5)=O)C)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Balwierczak JL, et al. Characterization of a potent and selective endothelin-B receptor antagonist, IRL 2500.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S393-6. [Content Brief]
[2]. Webb RL, et al. Effects of the ETB-selective antagonist IRL 2500 in conscious spontaneously hypertensive and Wistar-Kyoto rats.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S389-92. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IRL 2500 (Standard) Related Classifications
HY-103460R Related Classifications
Powered by Bioz