N-Methyltyramine hydrochloride

Cat. No.: HY-W153159 Purity: 99.41%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N-Methyltyramine (hydrochloride) can be isolated from the plants of the Citrus genus.

For research use only. We do not sell to patients.

N-Methyltyramine hydrochloride Chemical Structure

CAS No. : 13062-76-5

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1 g	USD 80	In-stock	Estimated Time of Arrival: December 31
5 g	USD 180	In-stock	Estimated Time of Arrival: December 31
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Description

N-Methyltyramine (hydrochloride) can be isolated from the plants of the Citrus genus.

Molecular Weight

187.67

Formula

C₉H₁₄ClNO

CAS No.

13062-76-5

Appearance

Solid

Color

White to off-white

SMILES

CNCCC1=CC=C(O)C=C1.Cl

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (532.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 25 mg/mL (133.21 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3285 mL	26.6425 mL	53.2850 mL
5 mM	1.0657 mL	5.3285 mL	10.6570 mL
10 mM	0.5329 mL	2.6643 mL	5.3285 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (13.32 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (13.32 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (13.32 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.41%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (245 KB) HNMR (231 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

References

[1]. Luigi Servillo, et al. N-methylated derivatives of tyramine in citrus genus plants: identification of N,N,N-trimethyltyramine (candicine). J Agric Food Chem. 2014, 62, 12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	5.3285 mL	26.6425 mL	53.2850 mL	133.2126 mL
	5 mM	1.0657 mL	5.3285 mL	10.6570 mL	26.6425 mL
	10 mM	0.5329 mL	2.6643 mL	5.3285 mL	13.3213 mL
	15 mM	0.3552 mL	1.7762 mL	3.5523 mL	8.8808 mL
	20 mM	0.2664 mL	1.3321 mL	2.6643 mL	6.6606 mL
	25 mM	0.2131 mL	1.0657 mL	2.1314 mL	5.3285 mL
	30 mM	0.1776 mL	0.8881 mL	1.7762 mL	4.4404 mL
	40 mM	0.1332 mL	0.6661 mL	1.3321 mL	3.3303 mL
	50 mM	0.1066 mL	0.5329 mL	1.0657 mL	2.6643 mL
	60 mM	0.0888 mL	0.4440 mL	0.8881 mL	2.2202 mL
	80 mM	0.0666 mL	0.3330 mL	0.6661 mL	1.6652 mL
	100 mM	0.0533 mL	0.2664 mL	0.5329 mL	1.3321 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N-Methyltyramine hydrochloride