2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Clonidine

Clonidine 

Cat. No.: HY-12721 Purity: 99.81%
COA Handling Instructions

Clonidine is an alpha 2-adrenergic agonist.

For research use only. We do not sell to patients.

Clonidine Chemical Structure

Clonidine Chemical Structure

CAS No. : 4205-90-7

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 110 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 110 In-stock
Solid
50 mg USD 100 In-stock
100 mg USD 160 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Clonidine:

Clonidine Related Antibodies

Top Publications Citing Use of Products

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α adrenergic receptor β adrenergic receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Clonidine is an alpha 2-adrenergic agonist[1].

IC50 & Target

alpha 2-adrenergic[1]
In Vitro

Clonidine suppresses the firing activity of neurons[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clonidine Related Antibodies
Clinical Trial
Molecular Weight

230.09

Appearance

Solid

Formula

C9H9Cl2N3
CAS No.
SMILES

ClC1=C(NC2=NCCN2)C(Cl)=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (434.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3461 mL 21.7306 mL 43.4613 mL
5 mM 0.8692 mL 4.3461 mL 8.6923 mL
10 mM 0.4346 mL 2.1731 mL 4.3461 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (10.87 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.87 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.87 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.93%

COA (253 KB) HNMR (114 KB) RP-HPLC (182 KB)

Handling Instructions (2659 KB)
References
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Clonidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Clonidine4205-90-7Adrenergic ReceptorBeta Receptoranesthesiaα2-adrenergicInhibitorinhibitorinhibit

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