N-Methyltyramine (Standard)
N-Methyltyramine (Standard) is the analytical standard of N-Methyltyramine (HY-W153897). This product is intended for research and analytical applications. N-Methyltyramine is an orally active α2-adrenoreceptor antagonist with an IC50 value of 5.53 μM against rat targets. N-Methyltyramine blocks α2-adrenoreceptors, while inhibiting lipolysis, hyperactivity responses and small intestinal peristalsis in mice. N-Methyltyramine promotes gastrin release and pancreatic juice secretion, upregulates appetite, blood pressure, myocardial contraction frequency and contraction intensity, and increases renal blood flow, renal vascular resistance and mean peripheral arterial resistance. N-Methyltyramine relaxes mouse small intestinal smooth muscle and undergoes biotransformation in vivo to produce adrenaline. N-Methyltyramine can be used in studies related to gastrointestinal diseases.
For research use only. We do not sell to patients.
- CAS No.: 370-98-9
- Formula: C9H13NO
- Molecular Weight:151.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 370-98-9
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Molecular Weight 151.21
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Formula C9H13NO
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SMILES
CNCCC1=CC=C(C=C1)O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Stohs SJ, et al. A review of the receptor binding and pharmacological effects of N-methyltyramine. Phytother Res. 2015 Jan;29(1):14-6. [Content Brief]
[2]. Ni J, et al. Effect of N-methyltyramine on the regulation of adrenergic receptors via enzymatic epinephrine synthesis for the treatment of gastrointestinal disorders. Biomed Pharmacother. 2019 Mar;111:1393-1398. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)