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Results for "

ribonucleoside

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Antibiotic (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (1) Endogenous Metabolite (4) Enterovirus (1) Flavivirus (1) Fluorescent Dye (1) HCV (1) Influenza Virus (2) Nucleoside Antimetabolite/Analog (3) Parasite (2) SARS-CoV (3) Topoisomerase (1)
By Research Areas:	Cancer (1) Infection (5) Inflammation/Immunology (3) Metabolic Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-24400

Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside	Biochemical Assay Reagents	Others
Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside is a biochemical reagent that can be used for compound synthesis .

HY-W011793

4-Thiouridine	Others	Others
4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response .

HY-146744

Antileishmanial agent-4

Parasite Infection

Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent .

Antileishmanial agent-4	Parasite	Infection
Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent .

HY-146745

Antileishmanial agent-5	Parasite	Inflammation/Immunology
Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent. Antileishmanial agent-4 is against L.infantum and T.cruzi with EC₅₀ values of 0.68 μM and 0.83 μM, respectively .

HY-121071

Ascamycin	Bacterial Nucleoside Antimetabolite/Analog Antibiotic	Infection
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against *Xanthomonas* species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for *Xanthomonas citri, Xanthomonas oryzae* and *Mycobacterium phlei*, respectively .

HY-N8060

Orotidine 5′-monophosphate Orotidine monophosphate; Orotidylic acid	Endogenous Metabolite	Others
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase .

HY-43059

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 5'-O-DMT-2'-O-TBDMS-ibu-rG	Nucleoside Antimetabolite/Analog	Others
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides .

HY-101984

N6,N6-Dimethyladenosine 2 Publications Verification	Nucleoside Antimetabolite/Analog	Inflammation/Immunology
N6,N6-Dimethyladenosine is a modified ribonucleoside previously found in rRNA, and also exhibits in mycobacterium bovis Bacille Calmette-Guérin tRNA .

HY-127137

Adenylosuccinic acid Adenylosuccinate; Aspartyl adenylate	Endogenous Metabolite	Metabolic Disease
Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD) .

HY-127137A

Adenylosuccinic acid tetraammonium Adenylosuccinate tetraammonium; Aspartyl adenylate tetraammonium	Endogenous Metabolite	Metabolic Disease
Adenylosuccinic acid tetraammonium (Adenylosuccinate; Aspartyl adenylate) is an orally active purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid tetraammonium can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid tetraammonium has the potential for the study of duchenne muscular dystrophy(DMD) .

HY-103400

8-Chloroadenosine 8-Cl-Ado	AMPK Autophagy	Cancer
8-Chloroadenosine (8-Cl-Ado), a unique ribonucleoside analog, depletes endogenous ATP that subsequently induces the phosphorylation and activation of AMPK. 8-Chloroadenosine induces autophagic cell death. 8-Chloroadenosine effectively inhibited in vivo tumor growth in mice .

HY-135853

Molnupiravir Maximum Cited Publications 38 Publications Verification EIDD-2801; MK-4482	SARS-CoV Influenza Virus	Infection
Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza .

HY-156832F

5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT	Fluorescent Dye	Others
5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT is a double-stranded ribonucleoside modified by the fluorescent molecule 5'6-FAM. 5'6-FAM is a mixture consisting of 5-FAM (HY-66022) and 6-FAM (HY-66021). Ex/Em of 5-FAM = 490 nm/520 nm .

HY-135867D

NHC-diphosphate 1 Publications Verification	Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV	Infection
NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) .

HY-W015764

T-1105 1 Publications Verification	Flavivirus	Infection
T-1105, a structural analogue of T-705, is a novel broad-spectrum viral polymerase inhibitor. T-1105 inhibits the polymerases of RNA viruses after being converted to ribonucleoside triphosphate (RTP) metabolite. T-1105 has antiviral activity against various RNA viruses. T-1105 can be formed by nicotinamide mononucleotide adenylyltransferase .

HY-135853S

Molnupiravir-d7 EIDD-2801-d₇; MK-4482-d₇	SARS-CoV Influenza Virus	Inflammation/Immunology
Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT	Fluorescent Dyes/Probes
5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT is a double-stranded ribonucleoside modified by the fluorescent molecule 5'6-FAM. 5'6-FAM is a mixture consisting of 5-FAM (HY-66022) and 6-FAM (HY-66021). Ex/Em of 5-FAM = 490 nm/520 nm .

Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside	Biochemical Assay Reagents
Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside is a biochemical reagent that can be used for compound synthesis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-135867D

NHC-diphosphate 1 Publications Verification	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Enterovirus HCV Topoisomerase SARS-CoV
NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a diphosphate form . NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV) .

HY-121071

Ascamycin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Nucleoside Antimetabolite/Analog Antibiotic
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against *Xanthomonas* species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for *Xanthomonas citri, Xanthomonas oryzae* and *Mycobacterium phlei*, respectively .

HY-N8060

Orotidine 5′-monophosphate Orotidine monophosphate; Orotidylic acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase .

HY-127137

Adenylosuccinic acid Adenylosuccinate; Aspartyl adenylate	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD) .

Species:	Human (3) E.coli (1)
Tag:	His (4) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71267

	RRM2 Protein, Human (HEK293, His) ribonucleoside-Diphosphate Reductase Subunit M2; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RRM2; RR2	Human	HEK293
	RRM2 Protein, pivotal in DNA synthesis, catalyzes deoxyribonucleotide biosynthesis from ribonucleotide precursors, ensuring vital building blocks for DNA replication. Beyond nucleotide biosynthesis, RRM2 inhibits Wnt signaling, indicating involvement in regulating this crucial cellular pathway. RRM2 Protein, Human (HEK293, His) is the recombinant human-derived RRM2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of RRM2 Protein, Human (HEK293, His) is 389 a.a., with molecular weight of ~47.0 kDa.

HY-P74591

	RRM1 Protein, Human (sf9, His-GST) ribonucleoside-diphosphate reductase large subunit; RRM1; RR1	Human	Sf9 insect cells
	RRM1 Protein, crucial for DNA synthesis, catalyzes the biosynthesis of deoxyribonucleotides from ribonucleotide precursors. Its enzymatic activity is essential, providing building blocks for accurate and efficient DNA replication. RRM1 Protein, Human (sf9, His-GST) is the recombinant human-derived RRM1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of RRM1 Protein, Human (sf9, His-GST) is 792 a.a., with molecular weight of ~98 kDa.

HY-P76534

	p53R2 Protein, Human (His) ribonucleoside-diphosphate reductase subunit M2 B; p53R2; RRM2B	Human	E. coli
	The p53R2 protein is essential for cell survival and operates in a p53/TP53-dependent manner to support DNA repair. It provides essential deoxyribonucleotides for DNA repair, particularly in G1 or G2 arrested cells, and contains an iron-tyrosyl radical center critical for catalysis. p53R2 Protein, Human (His) is the recombinant human-derived p53R2 protein, expressed by E. coli , with N-His labeled tag. The total length of p53R2 Protein, Human (His) is 351 a.a., with molecular weight of ~43 kDa.

HY-P71704

	NrdD Protein, E.coli (His) nrdD; b4238; JW4197; Anaerobic ribonucleoside-triphosphate reductase	E.coli	E. coli
	The NrdD protein plays a key role in cellular processes by catalyzing the conversion of ribonucleotides into deoxyribonucleotides, an essential component required for DNA synthesis and repair. Various studies have demonstrated that NrdD contributes to the maintenance and replication of genetic material by promoting the conversion of ribonucleotides into their deoxyribonucleotide counterparts through its enzymatic activity. NrdD Protein, E.coli (His) is the recombinant E. coli-derived NrdD protein, expressed by E. coli , with N-His labeled tag. The total length of NrdD Protein, E.coli (His) is 712 a.a., with molecular weight of ~84.0 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-135853S

Molnupiravir-d7
Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

Molnupiravir-d7

Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

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