Antileishmanial agent-5
Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent. Antileishmanial agent-4 is against L.infantum and T.cruzi with EC50 values of 0.68 μM and 0.83 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2922333-29-5
- Formula: C17H17ClN4O4
- Molecular Weight:376.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Leishmania |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | CC50 |
>64 μM
Compound: 32
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Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence analysis
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence analysis
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[PMID: 35533570] |
| Peritoneal macrophage | CC50 |
>64 μM
Compound: 32
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Cytotoxicity against Swiss mouse peritoneal macrophages assessed as reduction in cell viability measured after 5 days by microscopic analysis
Cytotoxicity against Swiss mouse peritoneal macrophages assessed as reduction in cell viability measured after 5 days by microscopic analysis
|
[PMID: 35533570] |
Chemical Information
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CAS No. 2922333-29-5
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Molecular Weight 376.79
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Formula C17H17ClN4O4
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SMILES
CC1=NC=NC2=C1C(C3=NC=CC(Cl)=C3)=CN2[C@@H]4O[C@@H]([C@H]([C@H]4O)O)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)