subsp,

By Targets:	ADC Cytotoxin (1) Antibiotic (2) Bacterial (5) Biochemical Assay Reagents (1) Fungal (1) Interleukin Related (1) Mitochondrial Metabolism (1) Molecular Glues (1) PARP (1)
By Research Areas:	Cancer (3) Infection (4) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5009

Thermopsine	Bacterial	Infection
Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity .

HY-118893

Asukamycin	Antibiotic Bacterial Fungal Molecular Glues	Infection Cancer
Asukamycin, a manumycin-type metabolite, could be isolated from Streptomyces nodosus subsp. asukaensis. Asukamycin is an antibiotic and has antimicrobial activity. Asukamycin inhibits growth of various tumor cell lines .

HY-N1673

2,5-Dihydroxybenzaldehyde Gentisaldehyde	Bacterial	Infection
2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of **Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus** strains with a MIC₅₀ of 500 mg/L .

HY-N11094

Isopimarol acetate

Others Others

Isopimarol acetate is a natural product that can be found in Nepeta tuberosa subsp. Reticulate .

Isopimarol acetate	Others	Others
Isopimarol acetate is a natural product that can be found in Nepeta tuberosa subsp. Reticulate .

HY-N8673

3-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one	Others	Others
3-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one is derived from natural Scilla nervosa subsp. rigidifolia of isoflavone compounds .

HY-P2957

Hyaluronate lyase	Biochemical Assay Reagents	Metabolic Disease
Hyaluronate lyase can cleat hyaluronate (HA) and produce unsaturated disaccharides through a β-elimination reaction. The resulting disaccharides further trigger the downstream pathway and catalyze the next reaction. Hyaluronate lyase helps Streptococcus dysgalactiae subsp.equisimilis (SDSE) acquire nutrients from the host, causing bacterial pathogenicity .

HY-121497

3-Methoxybenzamide 3-MBA	PARP Bacterial	Cancer
3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .

HY-N1872

4-(3,4-Dihydroxyphenyl)butan-2-one
4-(3, 4-dihydroxyphenyl)butan-2-one is a compound isolated from the subspecies Lactobacillus plantarum subsp. argentoratensis. 4-(3, 4-dihydroxyphenyl)butan-2-one has antioxidant and anti-inflammatory activity. 4-(3, 4-dihydroxyphenyl)butan-2-one can be used for research of microbial fermentation .

HY-114936

Piericidin A AR-054	Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism	Infection Neurological Disease Cancer
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

HY-N0976

1,11b-Dihydro-11b-hydroxymedicarpin 11b-Hydroxy-11b,1-dihydromedicarpin	Interleukin Related	Inflammation/Immunology
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .

Cat. No.	Product Name	Type

HY-P2957

Hyaluronate lyase	Biochemical Assay Reagents
Hyaluronate lyase can cleat hyaluronate (HA) and produce unsaturated disaccharides through a β-elimination reaction. The resulting disaccharides further trigger the downstream pathway and catalyze the next reaction. Hyaluronate lyase helps Streptococcus dysgalactiae subsp.equisimilis (SDSE) acquire nutrients from the host, causing bacterial pathogenicity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5009

Thermopsine	Infection Alkaloids Classification of Application Fields Leguminosae Source classification Pyridine Alkaloids Plants Thermopsis lanceolala R.Br. Disease Research Fields	Bacterial
Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity .

HY-118893

Asukamycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Fungal Molecular Glues
Asukamycin, a manumycin-type metabolite, could be isolated from Streptomyces nodosus subsp. asukaensis. Asukamycin is an antibiotic and has antimicrobial activity. Asukamycin inhibits growth of various tumor cell lines .

HY-N1673

2,5-Dihydroxybenzaldehyde Gentisaldehyde	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Disease Research Fields	Bacterial
2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of **Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus** strains with a MIC₅₀ of 500 mg/L .

HY-N11094

Isopimarol acetate	Structural Classification Coreopsis lanceolata L. Terpenoids Labiatae Source classification Diterpenoids Plants	Others
Isopimarol acetate is a natural product that can be found in Nepeta tuberosa subsp. Reticulate .

HY-N8673

3-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one	Structural Classification Monophenols Flavonoids Source classification Phenols Plants Other Flavonoids Barnardia japonica (Thunberg) Schultes & J. H. Schultes Asparagaceae Juss.	Others
3-(4-Hydroxybenzylidene)-5-hydroxy-7-methoxychroman-4-one is derived from natural Scilla nervosa subsp. rigidifolia of isoflavone compounds .

HY-114936

Piericidin A AR-054	Structural Classification Neurological Disease Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Anticancer Disease Research Fields	Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

HY-N0976

1,11b-Dihydro-11b-hydroxymedicarpin 11b-Hydroxy-11b,1-dihydromedicarpin	Structural Classification Natural Products Classification of Application Fields Leguminosae Source classification Derris robusta Plants Inflammation/Immunology Disease Research Fields	Interleukin Related
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .

Tag:	His (3) Tag Free (1) Strep (1)
Source:	E. coli Cell-free (2) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P702358

	*Lgt Protein, Lactococcus lactis subsp. lactis (Cell-Free, His)* Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase	Others	E. coli Cell-free
	Lgt protein is a key enzyme that catalyzes key steps in triacylglycerol synthesis using diacylglycerol and fatty acyl-CoA. Lgt is highly expressed in small intestinal epithelial cells and is critical for dietary fat absorption. Lgt Protein, Lactococcus lactis subsp. lactis (Cell-Free, His) is the recombinant Lgt protein, expressed by E. coli Cell-free , with C-6*His labeled tag. The total length of Lgt Protein, Lactococcus lactis subsp. lactis (Cell-Free, His) is 261 a.a., with molecular weight of 32.6 kDa.

HY-P702407

	*Os03g0263600 Protein, Oryza sativa subsp. japonica (Cell-Free, His)* Os03g0263600 protein	Others	E. coli Cell-free
	The Os03g0263600 protein is an important member of the saosidine synthase family and plays a crucial role in plant alkaloid biosynthesis by catalyzing the formation of saosidine. Its research enhances the understanding of plant defense mechanisms and has potential applications in crop improvement. Os03g0263600 Protein, Oryza sativa subsp. japonica (Cell-Free, His) is the recombinant Os03g0263600 protein, expressed by E. coli Cell-free , with N-6*His labeled tag. The total length of Os03g0263600 Protein, Oryza sativa subsp. japonica (Cell-Free, His) is 427 a.a., with molecular weight of 51.8 kDa.

HY-P701933

	*ADH II Protein, Zymomonas mobilis subsp. mobilis* adhB; Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II	Others	E. coli
	ADH II Protein, an iron-dependent alcohol dehydrogenase, is pivotal in converting pyruvate to ethanol. This enzymatic activity is essential for pathways involving ethanol formation, contributing to physiological processes in alcohol metabolism. Its iron dependency underscores intricate biochemical mechanisms, emphasizing ADH II's significance in producing ethanol from pyruvate within relevant biological contexts. ADH II Protein, Zymomonas mobilis subsp. mobilis is the recombinant ADH II protein, expressed by E. coli , with tag free. The total length of ADH II Protein, Zymomonas mobilis subsp. mobilis is 382 a.a., .

HY-P701934

	*ADH II Protein, Zymomonas mobilis subsp. mobilis (His, Strep)* adhB; Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II	Others	E. coli
	ADH II Protein, an iron-dependent alcohol dehydrogenase, is pivotal in converting pyruvate to ethanol. This enzymatic activity is essential for pathways involving ethanol formation, contributing to physiological processes in alcohol metabolism. Its iron dependency underscores intricate biochemical mechanisms, emphasizing ADH II's significance in producing ethanol from pyruvate within relevant biological contexts. ADH II Protein, Zymomonas mobilis subsp. mobilis (His, Strep) is the recombinant ADH II protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of ADH II Protein, Zymomonas mobilis subsp. mobilis (His, Strep) is 382 a.a., .


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