1. Cell Cycle/DNA Damage
    Epigenetics
  2. PARP
  3. 3-Methoxybenzamide

3-Methoxybenzamide (Synonyms: 3-MBA)

Cat. No.: HY-121497
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3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum).

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3-Methoxybenzamide Chemical Structure

3-Methoxybenzamide Chemical Structure

CAS No. : 5813-86-5

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Description

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2].

In Vitro

3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation[1].
3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants[2].

Cell Viability Assay[1]

Cell Line: ftsZ mutant strains.
Concentration: 0-30 mM.
Incubation Time: 30℃ overnight.
Result: Changes directly or indirectly the ability of ftsZ to bind or hydrolyze the guanine nucleotide, ultimately leading to the inhibition of Zring formation.
Molecular Weight

151.16

Formula

C₈H₉NO₂

CAS No.

5813-86-5

SMILES

O=C(N)C1=CC=CC(OC)=C1

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Keywords:

3-Methoxybenzamide3-MBAPARPpoly ADP ribose polymeraseADPRTFtsZmicrotuberInhibitorinhibitorinhibit

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3-Methoxybenzamide
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