1. Cell Cycle/DNA Damage
    Epigenetics
    Anti-infection
  2. PARP
    Bacterial
  3. 3-Methoxybenzamide

3-Methoxybenzamide  (Synonyms: 3-MBA)

Cat. No.: HY-121497 Purity: 99.40%
COA Handling Instructions

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum).

For research use only. We do not sell to patients.

3-Methoxybenzamide Chemical Structure

3-Methoxybenzamide Chemical Structure

CAS No. : 5813-86-5

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Based on 1 publication(s) in Google Scholar

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Description

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2].

In Vitro

3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation[1].
3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: ftsZ mutant strains.
Concentration: 0-30 mM.
Incubation Time: 30℃ overnight.
Result: Changes directly or indirectly the ability of ftsZ to bind or hydrolyze the guanine nucleotide, ultimately leading to the inhibition of Zring formation.
Molecular Weight

151.16

Formula

C8H9NO2

CAS No.
SMILES

O=C(N)C1=CC=CC(OC)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (661.55 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6155 mL 33.0775 mL 66.1551 mL
5 mM 1.3231 mL 6.6155 mL 13.2310 mL
10 mM 0.6616 mL 3.3078 mL 6.6155 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.40%

References
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Product Name:
3-Methoxybenzamide
Cat. No.:
HY-121497
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