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Results for "

uricosuric

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (1) COX (4) Cytochrome P450 (2) Dihydroorotate Dehydrogenase (1) Drug Derivative (1) Endogenous Metabolite (4) Fungal (1) GLUT (1) Isotope-Labeled Compounds (2) OAT (3) Potassium Channel (1) PPAR (1) Reference Standards (2) Sodium Channel (1) URAT1 (4) Wnt (1) Xanthine Oxidase (1) β-catenin (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Endocrinology (1) Infection (2) Inflammation/Immunology (12) Metabolic Disease (9)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18342

Diflunisal 1 Publications Verification MK-647	COX	Inflammation/Immunology Cancer
Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-B1271

Sulfinpyrazone 4 Publications Verification G-28315	Endogenous Metabolite	Inflammation/Immunology
Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .

HY-U00242

Indacrinone MK-196; Indacrynic acid	Biochemical Assay Reagents	Metabolic Disease
Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee.

HY-B1271R

Sulfinpyrazone (Standard) G-28315 (Standard)	Reference Standards Endogenous Metabolite	Inflammation/Immunology
Sulfinpyrazone (Standard) is the analytical standard of Sulfinpyrazone. This product is intended for research and analytical applications. Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .

HY-111345

Epaminurad UR-1102; URC-102	OAT URAT1	Metabolic Disease Inflammation/Immunology
Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a K_i of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research .

HY-U00048

Bucolome Paramidin; Paramidine	Cytochrome P450	Inflammation/Immunology
Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent.

HY-18342S

Diflunisal-d3 MK-647-d₃	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
Diflunisal-d₃ is the deuterium labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-155948

Uricosuric agent-1	Endogenous Metabolite	Cancer
Uricosuric agent-1 (KT-433) is an uricosuric agent .

HY-111345A

Epaminurad hydrochloride UR-1102 hydrochloride; URC-102 hydrochloride	OAT URAT1	Metabolic Disease Inflammation/Immunology
Epaminurad (UR-1102) hydrochloride is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a K_i of 0.057 μM. Epaminurad hydrochloride quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad hydrochloride is a uricosuric agent. Epaminurad hydrochloride can be used for gout and hyperuricemia research .

HY-144305

KPH2f	URAT1 GLUT	Infection
KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC₅₀s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC₅₀=32.14 and 26.74 μM) .

HY-106333

Irtemazole R 60844	Fungal	Infection Inflammation/Immunology
Irtemazole is an orally active antifungal agent. Irtemazole possesses uricosuric effect. Irtemazole is used in the research for blastomycosis, histoplasmosis, and aspergillosis .

HY-119453

Oxycinchophen	Dihydroorotate Dehydrogenase	Metabolic Disease Inflammation/Immunology
Oxycinchophen exhibits anti-inflammatory and uricosuric activity. Oxycinchophen displaces urate from albumin, exhibits high affinity for the DNSA-binding site on the albumin molecule .

HY-17482

Difenpiramide Z-876	Drug Derivative	Inflammation/Immunology
Difenpiramide (Z-876) is a bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties. Difenpiramide has platelet anti-aggregation activity .

HY-111181

A 56234	Sodium Channel Potassium Channel	Metabolic Disease
A 56234 is an orally active benzisoxazole diuretic. A 56234 produces dose-dependent diuresis, sodium and chloride excretion, significantly increases potassium excretion, and also slightly increases calcium, magnesium, and total protein excretion. A 56234 has shown uricosuric effects in animal studies

HY-B0939

Etebenecid	Bacterial	Metabolic Disease
Etebenecid is a uricosuric agent that also inhibits the renal tubular secretion of penicillin.

HY-106300

AA 193	Others	Cardiovascular Disease
AA 193 is a uricosuric agent. AA 193 increases urate excretion in hyperuricemic rats .

HY-18342R

Diflunisal (Standard) MK-647 (Standard)	Reference Standards COX	Inflammation/Immunology Cancer
Diflunisal (Standard) is the analytical standard of Diflunisal. This product is intended for research and analytical applications. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-18342S1

Diflunisal-13C6 MK-647-¹³C₆	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
Diflunisal- ¹³C₆ (MK-647- ¹³C₆) is ¹³C labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-14998

Halofenate MK 185	β-catenin PPAR Wnt	Endocrinology
Halofenate, structurally akin to clofibrate, was evaluated in hypertriglyceridemic patients over 6-week periods in a controlled, double-blind crossover trial. It effectively reduced serum triglycerides by 50%, with minimal impact on serum cholesterol levels. Additionally, it lowered serum uric acid by 30% and exhibited uricosuric effects independent of glomerular filtration rate. Halofenate was associated with a significant increase in plasma thyroxine (T4), accompanied by a decrease in protein-bound iodine and T4 by column. In vitro studies confirmed its ability to displace T4 from thyroid-binding proteins, suggesting a thyroxine-displacing effect, which could influence thyroid function in vivo .

HY-N17914

Smilaxchinoside A	Xanthine Oxidase	Metabolic Disease
Smilaxchinoside A is an orally active steroidal glycoside found in the roots of S. riparia. Smilaxchinoside A reduces serum uric acid levels and shows potent uricosuric activity. Smilaxchinoside A inhibits XOD activity and downregulates renal mURAT1 expression. Smilaxchinoside A can be used for the research of hyperuricemia .

HY-180227

URAT1-IN-15	URAT1 OAT Cytochrome P450	Metabolic Disease
URAT1-IN-15 (Compound 9) is an orally active, selective URAT1 inhibitor with an IC₅₀ of 69.81 nM. URAT1-IN-15 inhibits CYP2C9 (IC₅₀ = 8.39 μM). URAT1-IN-15 shows uricosuric activity. URAT1-IN-15 can be used in the research of hyperuricemia .

HY-113724

S-8666	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
S-8666 is an orally active uricosuric antihypertensive diuretic. The S-8666 has both S-(-)- and R-(+)-isomers. The diuretic and sodium-excretion activities of it are entirely dominated by the S-(-)-isomer, while the R-(+)-isomer shows no significant activity. S-8666 relies on the organic acid transport system to be secreted through the proximal tubule. S-8666 exhibits a clear uric acid excretion-promoting activity and diuretic effect in various species (such as rats and chimpanzees) .

Irtemazole R 60844	Biochemical Assay Reagents
Irtemazole is an orally active antifungal agent. Irtemazole possesses uricosuric effect. Irtemazole is used in the research for blastomycosis, histoplasmosis, and aspergillosis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1271

Sulfinpyrazone 4 Publications Verification G-28315	Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .

HY-B1271R

Sulfinpyrazone (Standard) G-28315 (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Sulfinpyrazone (Standard) is the analytical standard of Sulfinpyrazone. This product is intended for research and analytical applications. Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .

HY-N17914

Smilaxchinoside A	Structural Classification Smilacaceae Smilax riparia A. DC. Plants Steroids Source Classification	Xanthine Oxidase
Smilaxchinoside A is an orally active steroidal glycoside found in the roots of S. riparia. Smilaxchinoside A reduces serum uric acid levels and shows potent uricosuric activity. Smilaxchinoside A inhibits XOD activity and downregulates renal mURAT1 expression. Smilaxchinoside A can be used for the research of hyperuricemia .

Cat. No.	Product Name	Chemical Structure

HY-18342S

Diflunisal-d3
Diflunisal-d₃ is the deuterium labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-18342S1

Diflunisal-13C6
Diflunisal- ¹³C₆ (MK-647- ¹³C₆) is ¹³C labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

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uricosuric

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products