24 Results for "

uricosuric

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "uricosuric" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-B1271
CAS No.: 57-96-5
Synonyms: G-28315
Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-18342
CAS No.: 22494-42-4
Synonyms: MK-647
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.
loading...
    loading...
Cat. No.: HY-U00242
CAS No.: 56049-88-8
Synonyms: MK-196; Indacrynic acid
Research Areas:  

Metabolic Disease

Indacrinone (MK196) is an investigational diuretic which has pronounced saluretic activity in the rat and dog as well as both uricosuric and saluretic activity in the chimpanzee.
loading...
    loading...
Cat. No.: HY-B1271R
CAS No.: 57-96-5
Synonyms: G-28315 (Standard)
Sulfinpyrazone (Standard) is the analytical standard of Sulfinpyrazone. This product is intended for research and analytical applications. Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .
loading...
    loading...
Cat. No.: HY-111345
CAS No.: 1198153-15-9
Purity:  99.75%
Synonyms: UR-1102; URC-102
Target:  

OAT URAT1

Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research .
loading...
    loading...
Cat. No.: HY-U00048
CAS No.: 841-73-6
Synonyms: Paramidin; Paramidine
Target:  

Cytochrome P450

Research Areas:  

Inflammation/Immunology

Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent.
loading...
    loading...
Cat. No.: HY-18342S
CAS No.: 1286107-99-0
Synonyms: MK-647-d3
Diflunisal-d3 is the deuterium labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.
loading...
    loading...
Cat. No.: HY-155948
CAS No.: 91627-33-7
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Uricosuric agent-1 (KT-433) is an uricosuric agent .
loading...
    loading...
Cat. No.: HY-111345A
CAS No.: 1198153-46-6
Synonyms: UR-1102 hydrochloride; URC-102 hydrochloride
Target:  

OAT URAT1

Epaminurad (UR-1102) hydrochloride is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad hydrochloride quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad hydrochloride is a uricosuric agent. Epaminurad hydrochloride can be used for gout and hyperuricemia research .
loading...
    loading...
Cat. No.: HY-144305
CAS No.: 2760615-09-4
Purity:  99.22%
Target:  

URAT1 GLUT

Research Areas:  

Infection

KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM) .
loading...
    loading...
Cat. No.: HY-106333
CAS No.: 129369-64-8
Synonyms: R 60844
Irtemazole is an orally active antifungal agent. Irtemazole possesses uricosuric effect. Irtemazole is used in the research for blastomycosis, histoplasmosis, and aspergillosis .
loading...
    loading...
Cat. No.: HY-119453
CAS No.: 485-89-2
Oxycinchophen exhibits anti-inflammatory and uricosuric activity. Oxycinchophen displaces urate from albumin, exhibits high affinity for the DNSA-binding site on the albumin molecule .
loading...
    loading...
Cat. No.: HY-17482
CAS No.: 51484-40-3
Synonyms: Z-876
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Difenpiramide (Z-876) is a bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties. Difenpiramide has platelet anti-aggregation activity .
loading...
    loading...
Cat. No.: HY-111181
CAS No.: 90247-09-9
Research Areas:  

Metabolic Disease

A 56234 is an orally active benzisoxazole diuretic. A 56234 produces dose-dependent diuresis, sodium and chloride excretion, significantly increases potassium excretion, and also slightly increases calcium, magnesium, and total protein excretion. A 56234 has shown uricosuric effects in animal studies
loading...
    loading...
Cat. No.: HY-B0939
CAS No.: 1213-06-5
Target:  

Bacterial

Research Areas:  

Metabolic Disease

Etebenecid is a uricosuric agent that also inhibits the renal tubular secretion of penicillin.
loading...
    loading...
Cat. No.: HY-18342R
CAS No.: 22494-42-4
Synonyms: MK-647 (Standard)
Target:  

Reference Standards COX

Research Areas:  

Inflammation/Immunology Cancer

Diflunisal (Standard) is the analytical standard of Diflunisal. This product is intended for research and analytical applications. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.
loading...
    loading...
Cat. No.: HY-18342S1
Synonyms: MK-647-13C6
Diflunisal- 13C6 (MK-647- 13C6) is 13C labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.
loading...
    loading...
Cat. No.: HY-106300
CAS No.: 107804-48-8
AA 193 is an orally active uricosuric agent. AA 193 inhibits the net reabsorption of uric acid in nephrons, regulates the renal reabsorption process of filtered uric acid, promotes uric acid excretion in a dose-dependent manner, and reduces serum uric acid levels. AA 193 mildly inhibits the activity of xanthine dehydrogenase (XDH). AA 193 can be used in studies related to hyperuricemia .
loading...
    loading...
Cat. No.: HY-14998
CAS No.: 26718-25-2
Synonyms: MK 185
Target:  

β-catenin PPAR Wnt

Research Areas:  

Endocrinology

Halofenate, structurally akin to clofibrate, was evaluated in hypertriglyceridemic patients over 6-week periods in a controlled, double-blind crossover trial. It effectively reduced serum triglycerides by 50%, with minimal impact on serum cholesterol levels. Additionally, it lowered serum uric acid by 30% and exhibited uricosuric effects independent of glomerular filtration rate. Halofenate was associated with a significant increase in plasma thyroxine (T4), accompanied by a decrease in protein-bound iodine and T4 by column. In vitro studies confirmed its ability to displace T4 from thyroid-binding proteins, suggesting a thyroxine-displacing effect, which could influence thyroid function in vivo .
loading...
    loading...
Cat. No.: HY-111345R
CAS No.: 1198153-15-9
Synonyms: UR-1102 (Standard); URC-102 (Standard)
Epaminurad (Standard) is the analytical standard of Epaminurad (HY-111345). This product is intended for research and analytical applications. Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research .
loading...
    loading...