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Sulfinpyrazone (Synonyms: G-28315)

Cat. No.: HY-B1271 Purity: 98.01%
Handling Instructions

Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects.

For research use only. We do not sell to patients.

Sulfinpyrazone Chemical Structure

Sulfinpyrazone Chemical Structure

CAS No. : 57-96-5

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Based on 1 publication(s) in Google Scholar

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Description

Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects[1][2].

In Vitro

Sulfinpyrazone (G-28315) stimulates fibrinolytic activity[2].

In Vivo

In rats with kaolin-induced paw oedema, Sulfinpyrazone (G-28315) is able to restore the markedly prolonged euglobulin clot lysis time in an oral dose of 30 mg/kg. Beside these effects, Sulfinpyrazone protects rabbits from arachidonate-induced sudden death after a single oral dose of 10-30 mg/kg[2].

Molecular Weight

404.48

Formula

C₂₃H₂₀N₂O₃S

CAS No.

57-96-5

SMILES

O=C(C1CCS(C2=CC=CC=C2)=O)N(C3=CC=CC=C3)N(C4=CC=CC=C4)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

SulfinpyrazoneG-28315G28315G 28315OthersoraluricosuricintermittentgoutyarthritisantithromboticplateletInhibitorinhibitorinhibit

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Sulfinpyrazone
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