URAT1-IN-15
URAT1-IN-15 (Compound 9) is an orally active, selective URAT1 inhibitor with an IC50 of 69.81 nM. URAT1-IN-15 inhibits CYP2C9 (IC50 = 8.39 μM). URAT1-IN-15 shows uricosuric activity. URAT1-IN-15 can be used in the research of hyperuricemia.
For research use only. We do not sell to patients.
- Formula: C14H8Cl2N2O2
- Molecular Weight:307.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 69.81 nM (URAT1); 905 nM (OAT1); 724 nM (OAT3); 8.39 μM (CYP450 2C9)[1]
Chemical Information
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Molecular Weight 307.13
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Formula C14H8Cl2N2O2
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SMILES
O=C(N1C=NC2=CC=CC=C21)C3=CC(Cl)=C(C(Cl)=C3)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)