1. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  2. Drug-Linker Conjugates for ADC Topoisomerase
  3. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs.

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TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT 화학구조

CAS No. : 2857037-73-9

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제품 설명

TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs[1].

IC50 & Target[1]

Top1

 

분자량

717.79

화학식

C36H39N5O9S

CAS No.
SMILES

N(C([C@@H](NC([C@@H](NC(CS)=O)[C@H](C)C)=O)C)=O)C12CC(C1)(C2)C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=CC8=C(C7)OCO8

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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상품명:
TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
Cat. No.:
HY-171946
수량:
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