2857037-73-9
![TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-171946.gif "TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Chemical Structure")
Chemical Structure
TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
- CAS No.: 2857037-73-9
- Formula:C36H39N5O9S
- Molecular Weight:717.79
IUPAC Name: (S)-N-((S)-1-((3-((S)-7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-tetrahydro-10H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-14-yl)bicyclo[1.1.1]pentan-1-yl)amino)-1-oxopropan-2-yl)-2-(2-mercaptoacetamido)-3-methylbutanamide
InChIKey: UHINWHAJZURIAZ-JLVKPTLHSA-N
SMILES: N(C([C@@H](NC([C@@H](NC(CS)=O)[C@H](C)C)=O)C)=O)C12CC(C1)(C2)C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=CC8=C(C7)OCO8
Biological Activity: TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs[1].
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TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT | TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs. | |||||||||||||||||||||
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