2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. UCHL1-IN-1

UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research.

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UCHL1-IN-1

UCHL1-IN-1 Chemische Struktur

CAS. Nr. : 3068994-24-8

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UCHL1-IN-1 Related Antibodies

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USP1 USP2 USP4 USP7 USP8 USP10 USP21 USP30 UCHL1 USP11 USP15 USP28 USP25

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Beschreibung

UCHL1-IN-1 (Compound 46) is an inhibitor for Ubiquitin C-terminal Hydrolase L1 (UCHL1), with an IC50 of 5.1 μM. UCHL1-IN-1 can be used for cancer research[1].

IC50 & Target[1]

UCHL1

 

In Vitro

UCHL1-IN-1 (0-50 μM, 4 h) inhibits UCHL1 in BT549 cell[1].
UCHL1-IN-1 (0-50 μM, 24 h) inhibits cell migration and cell viability in BT549 cell[1].
UCHL1-IN-1 is relatively metabolically stable in human liver microsomes assay, with a t1/2 > 120 min, and low intrinsic hepatic clearance[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UCHL1-IN-1 Related Antibodies
Molekulargewicht

290.15

Formel

C11H13Cl2N3O2
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

ClCC(NNC(CN(C1=CC=C(C=C1)Cl)C)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reinheit & Dokumentation
Verweise
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UCHL1-IN-1 Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UCHL1-IN-13068994-24-8DeubiquitinaseDUBsBT549cell migrationInhibitorinhibitorinhibit

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