2. Immunology/Inflammation
  3. Interleukin Related
  4. Xeligekimab

Xeligekimab  (Synonyms: GR 1501)

Cat. No.: HY-P99515 Pureza: 95.00%
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Xeligekimab (GR 1501) is an anti-human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade. Xeligekimab can be used for the research of inflammatory disease, such as radiographic axial spondyloarthritis.

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No. CAS : 2382921-73-3

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Xeligekimab Related Antibodies

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Descripciòn

Xeligekimab (GR 1501) is an anti-human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade. Xeligekimab can be used for the research of inflammatory disease, such as radiographic axial spondyloarthritis[1].

Isotype

Human IgG4 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target[1]

IL-17A

 

In Vitro

Xeligekimab binds to and inhibits the activity of interleukin-17A and improves signs and symptoms of active radiographic axial spondyloarthritis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Xeligekimab Related Antibodies
Ensayo clínico
Gene ID

3605  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

145.66 kDa

No. CAS
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Xeligekimab]
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Pureza y Documentación
Referencias
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Xeligekimab Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Xeligekimab2382921-73-3GR 1501GR1501GR-1501Interleukin RelatedILIL-17AInterleukin-17Amonoclonal antibodyradiographic axial spondyloarthritisChinese patientsInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Xeligekimab
Cat. No.:
HY-P99515
Cantidad:
MCE Japan Authorized Agent:

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