2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. Endogenous Metabolite Nucleoside Antimetabolite/Analog
  4. 2'-Deoxyguanosine 5'-monophosphate disodium

2'-Deoxyguanosine 5'-monophosphate disodium  (Synonyms: 5′-dGMP disodium)

Cat. No.: HY-W013159 Purity: 99.85%
COA
SDS
Handling Instructions Technical Support

2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis.

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2'-Deoxyguanosine 5'-monophosphate disodium

2'-Deoxyguanosine 5'-monophosphate disodium 화학구조

CAS No. : 33430-61-4

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in Water 해외재고보유
Solid
100 mg 해외재고보유
500 mg 해외재고보유
1 g   견적 받기  
5 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of 2'-Deoxyguanosine 5'-monophosphate disodium:

2'-Deoxyguanosine 5'-monophosphate disodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 2'-Deoxyguanosine 5'-monophosphate disodium

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Human Endogenous Metabolite Microbial Metabolite

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis[1].

In Vitro

Guanine, the nucleobase of 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium, is the preferential DNA substrate of photooxidations via electron transfer or hydrogen abstraction (type I mechanism) and is the only DNA constituent that significantly reacts with 1O2 (type II mechanism). Therefore, molecules bearing guanine are good substrates to evaluate biologicallyrelevant photosensitizing properties[1].
2'-Deoxyguanosine 5'-monophosphate disodium can be used to evaluate the photosensitivity of lumazine (Lum). In the 2'-Deoxyguanosine 5'-monophosphate disodiumexperiments, the data revealed that 2'-Deoxyguanosine 5'-monophosphate indeed undergoes oxidation/oxygenation photoinduced by Lum[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2'-Deoxyguanosine 5'-monophosphate disodium Related Antibodies
분자량

391.18

화학식

C10H12N5Na2O7P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(O[Na])(O[Na])=O
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

용액&용해도
In Vitro: 

H2O : 111.11 mg/mL (284.04 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5564 mL 12.7818 mL 25.5637 mL
5 mM 0.5113 mL 2.5564 mL 5.1127 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (255.64 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.85%

SDS (396 KB)

COA (250 KB) HNMR (223 KB) RP-HPLC (274 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5564 mL 12.7818 mL 25.5637 mL 63.9092 mL
5 mM 0.5113 mL 2.5564 mL 5.1127 mL 12.7818 mL
10 mM 0.2556 mL 1.2782 mL 2.5564 mL 6.3909 mL
15 mM 0.1704 mL 0.8521 mL 1.7042 mL 4.2606 mL
20 mM 0.1278 mL 0.6391 mL 1.2782 mL 3.1955 mL
25 mM 0.1023 mL 0.5113 mL 1.0225 mL 2.5564 mL
30 mM 0.0852 mL 0.4261 mL 0.8521 mL 2.1303 mL
40 mM 0.0639 mL 0.3195 mL 0.6391 mL 1.5977 mL
50 mM 0.0511 mL 0.2556 mL 0.5113 mL 1.2782 mL
60 mM 0.0426 mL 0.2130 mL 0.4261 mL 1.0652 mL
80 mM 0.0320 mL 0.1598 mL 0.3195 mL 0.7989 mL
100 mM 0.0256 mL 0.1278 mL 0.2556 mL 0.6391 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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2'-Deoxyguanosine 5'-monophosphate disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-Deoxyguanosine 5'-monophosphate disodium33430-61-45′-dGMP disodiumEndogenous MetaboliteNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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상품명:
2'-Deoxyguanosine 5'-monophosphate disodium
Cat. No.:
HY-W013159
수량:
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