2. Cell Cycle/DNA Damage Anti-infection
  3. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Bacterial Influenza Virus
  4. 6-Azathymine

6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities.

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6-Azathymine

6-Azathymine 화학구조

CAS No. : 932-53-6

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
100 mg 해외재고보유
250 mg 해외재고보유
500 mg 해외재고보유
1 g   견적 받기  
5 g   견적 받기  

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6-Azathymine Related Antibodies

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  • 순도&문서

  • References

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제품 설명

6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities[1][2][3][4].

In Vitro

6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Azathymine Related Antibodies
In Vivo

The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5-14C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
분자량

127.10

화학식

C4H5N3O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1)NN=C(C)C1=O
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 125 mg/mL (983.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.8678 mL 39.3391 mL 78.6782 mL
5 mM 1.5736 mL 7.8678 mL 15.7356 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.8678 mL 39.3391 mL 78.6782 mL 196.6955 mL
5 mM 1.5736 mL 7.8678 mL 15.7356 mL 39.3391 mL
10 mM 0.7868 mL 3.9339 mL 7.8678 mL 19.6696 mL
15 mM 0.5245 mL 2.6226 mL 5.2452 mL 13.1130 mL
20 mM 0.3934 mL 1.9670 mL 3.9339 mL 9.8348 mL
25 mM 0.3147 mL 1.5736 mL 3.1471 mL 7.8678 mL
30 mM 0.2623 mL 1.3113 mL 2.6226 mL 6.5565 mL
40 mM 0.1967 mL 0.9835 mL 1.9670 mL 4.9174 mL
50 mM 0.1574 mL 0.7868 mL 1.5736 mL 3.9339 mL
60 mM 0.1311 mL 0.6557 mL 1.3113 mL 3.2783 mL
80 mM 0.0983 mL 0.4917 mL 0.9835 mL 2.4587 mL
100 mM 0.0787 mL 0.3934 mL 0.7868 mL 1.9670 mL
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6-Azathymine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Azathymine932-53-6Nucleoside Antimetabolite/AnalogDNA/RNA SynthesisBacterialInfluenza VirusD-3-aminoisobutyrate-pyruvateaminotransferasenucleobaseantiviralantibacterialDNAthymine6-nitrogenInhibitorinhibitorinhibit

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상품명:
6-Azathymine
Cat. No.:
HY-136559
수량:
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