2. Apoptosis Metabolic Enzyme/Protease
  3. Apoptosis Endogenous Metabolite
  4. Coenzyme Q9

Coenzyme Q9  (Synonyms: コエンザイムQ9; Ubiquinone Q9; CoQ9; Ubiquinone 9)

製品番号: HY-101415 純度: 99.77%
COA 取扱説明書 Technical Support

Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis.

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Coenzyme Q9

Coenzyme Q9 構造式

CAS 番号 : 303-97-9

容量 価格（税別） 在庫状況 数量
Solution
10 mM * 1 mL in Ethanol USD 462 在庫あり
Solid
1 mg $66 在庫あり
5 mg $264 在庫あり
10 mg $462 在庫あり
25 mg $924 在庫あり
50 mg $1386 在庫あり
100 mg $1945 在庫あり
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500 mg   お問い合わせ  

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Based on 1 publication(s) in Google Scholar

Other Forms of Coenzyme Q9:

Coenzyme Q9 関連抗体

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製品説明

Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体内実験

Coenzyme Q9 (5 mg/kg; p.o.; once a day for 4 weeks) reduces myocardial ischemia/reperfusion injury[2].
CoQ10 and CoQ9 are components of themitochondrial respiratory chain in mammals and can regulate some mitochondrial proteins/functions. Soybean, corn, and rapeseed oils are very rich sources of CoQ10, whereas CoQ9 has been found in high concentrations in corn oil[3].
The lack of a functional CoQ9 protein in homozygous CoQ9 mutant (CoQ9(X/X)) mice causes a severe reduction in the CoQ7 protein and a widespread CoQ deficiency and accumulation of demethoxyubiquinone. The deficit in CoQ induces a brain-specific impairment of mitochondrial bioenergetics performance, a reduction in respiratory control ratio, ATP levels and ATP/ADP ratio and specific loss of respiratory complex I. These effects lead to neuronal death and demyelinization with severe vacuolization and astrogliosis in the brain of CoQ9 (X/X) mice that consequently die between 3 and 6 months of age[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Hartley guinea pigs of about 350-400 g body weight[2]
Dosage: 5 mg/kg of body weight
Administration: P.o.; once a day for 4 weeks
Result: Nutritional supplementation of CoQ9 can reduce myocardial ischemia/reperfusion injury to the same extent as CoQ10.
分子量

795.23

分子式

C54H82O4
CAS 番号
Appearance

Solid

Color

Yellow to orange

SMILES

O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

Ethanol : 33.33 mg/mL (41.91 mM; ultrasonic and warming and heat to 50°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2575 mL 6.2875 mL 12.5750 mL
5 mM 0.2515 mL 1.2575 mL 2.5150 mL
10 mM 0.1257 mL 0.6287 mL 1.2575 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

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In Vivo Dissolution Calculator
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純度とドキュメンテーション

純度: 99.77%

COA (238 KB) HNMR (440 KB) RP-HPLC (268 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 1.2575 mL 6.2875 mL 12.5750 mL 31.4374 mL
5 mM 0.2515 mL 1.2575 mL 2.5150 mL 6.2875 mL
10 mM 0.1257 mL 0.6287 mL 1.2575 mL 3.1437 mL
15 mM 0.0838 mL 0.4192 mL 0.8383 mL 2.0958 mL
20 mM 0.0629 mL 0.3144 mL 0.6287 mL 1.5719 mL
25 mM 0.0503 mL 0.2515 mL 0.5030 mL 1.2575 mL
30 mM 0.0419 mL 0.2096 mL 0.4192 mL 1.0479 mL
40 mM 0.0314 mL 0.1572 mL 0.3144 mL 0.7859 mL
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Coenzyme Q9 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
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Keywords:

Coenzyme Q9303-97-9Ubiquinone Q9 CoQ9 Ubiquinone 9Coenzyme Q 9Coenzyme Q-9Ubiquinone Q 9Ubiquinone Q-9CoQ9CoQ 9CoQ-9Ubiquinone9Ubiquinone 9Ubiquinone-9ApoptosisEndogenous MetaboliterodentsamphipathicelectrontransportchainendogenousantioxidantleftventricularInhibitorinhibitorinhibit

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製品名:
Coenzyme Q9
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