2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1808
    Triprolidine 486-12-4 98.84%
    Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis.
    Triprolidine
  • HY-B1858
    Isoprothiolane 50512-35-1 99.91%
    Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver.
    Isoprothiolane
  • HY-B1866
    Linuron 330-55-2 99.88%
    Linuron is a phenylurea herbicide widely used to control the growth of grasses and weeds in various crops and orchards. Linuron acts as a photosystem II inhibitor. It also functions as a competitive androgen receptor (AR) antagonist, with an EC50 of 200 μM and a Ki of 100 μM against rat AR, and an EC50 of 20 μM against human AR. Linuron exhibits reproductive toxicity in animals and acts as an endocrine disruptor.\n
    Linuron
  • HY-B1984
    p,p'-DDD 72-54-8 99.37%
    p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats.
    p,p'-DDD
  • HY-B2091
    Azidocillin 17243-38-8
    Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases. Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azidocillin
  • HY-D0957
    Ethyl Violet 2390-59-2
    Ethyl Violet is a triphenylmethane cationic dye with antibacterial activity. Ethyl Violet is applicable to research related to antibacterial therapy and histological staining.
    Ethyl Violet
  • HY-N0306
    Hederasaponin B 36284-77-2 99.56%
    Hederasaponin B, isolated from Hedera helix, has broad-spectrum antiviral activity against various subgenotypes of Enterovirus 71 (EV71).
    Hederasaponin B
  • HY-N0465
    Olaquindox 23696-28-8 99.88%
    Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets.
    Olaquindox
  • HY-N0588
    Deapioplatycodin D 78763-58-3
    Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity.
    Deapioplatycodin D
  • HY-N0857
    Deoxyandrographolide 79233-15-1 98.0%
    Deoxyandrographolide is an orally active lactone found in the Andrographis paniculata Nees. Deoxyandrographolide shows a KD of 38.4 μM of HDAC1. Deoxyandrographolide enhances GLUT4 plasma membrane translocation, activates PI3K and AMPK-dependent signaling pathways, suppresses fasting blood glucose, serum insulin, triglycerides, and LDL-cholesterol levels. Deoxyandrographolide enhances HDAC1 expression via inhibited ubiquitination degradation, represses H3K4me3, improves chromosome stability, and restrains aging biomarkers p16, p21, γH2A.X, p53 and ROS production. Deoxyandrographolide interacts with Foot-and-Mouth Disease Virus 3Cpro active site, inhibits protease and IFN-antagonist activity, derepresses ISG expression, and inhibits viral replication. Deoxyandrographolide can be used for the researches of type 2 diabetes mellitus, vascular senescence and virus infection.
    Deoxyandrographolide
  • HY-N1073
    Wighteone 51225-30-0 98.71%
    Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFRL858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFRL858R/T790M mutation, and fungal infections.
    Wighteone
  • HY-N1407
    Polygalaxanthone III 162857-78-5 99.28%
    Polygalaxanthone III is a representative xanthone component of Polygala tenuifolia. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1, with an IC50 of 50.56 μM. Polygalaxanthone III repairs skin damage induced by M. furfur via activating STAT3 phosphorylation and exerts anti-inflammatory effects. Polygalaxanthone III can be used for research on M. furfur-related skin damage.
    Polygalaxanthone III
  • HY-N1416
    Pogostone 23800-56-8 99.81%
    Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy.
    Pogostone
  • HY-N1479
    Polygalic acid 1260-04-4 99.96%
    Polygalic acid is a polyphenolic acid with neuroprotective effects, and also an inhibitor of African swine fever virus polymerase (AsfvPolX), with an IC50 value of 5.05 μM. Polygalic acid alleviates neuroinflammation by regulating cholinergic activity, and its fecal level decreases in diseased mice. Polygalic acid can be used in research related to painful diabetic peripheral neuropathy complicated with cognitive impairment and African swine fever.
    Polygalic acid
  • HY-N1778
    3,4-Dimethoxycinnamic acid 2316-26-9 99.91%
    3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effects.
    3,4-Dimethoxycinnamic acid
  • HY-N2161
    Apiopaeonoside 100291-86-9 99.81%
    Apiopaeonoside is a natural product isolated from the root of Paeonia suffruticosa.
    Apiopaeonoside
  • HY-N2208
    4-Hydroxylonchocarpin 56083-03-5
    4-Hydroxylonchocarpin is a chalcone compound. 4-Hydroxylonchocarpin enhances the phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin induces reactive oxygen species (ROS) and apoptosis in liver cancer cells. 4-Hydroxylonchocarpin has various pharmacological activities, including antibacterial, anticancer, anti-retroviral, anti-tuberculosis, anti-malarial and anti-inflammatory activities.
    4-Hydroxylonchocarpin
  • HY-N2224
    Guaijaverin 22255-13-6 99.79%
    Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities.
    Guaijaverin
  • HY-N2357
    Eudesmin 526-06-7 99.96%
    Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities.
    Eudesmin
  • HY-N2377
    Allosecurinine 884-68-4 99.65%
    Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from Phyllanthus glaucus .
    Allosecurinine
Cat. No. Product Name / Synonyms Application Reactivity