2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P990811
    Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65))
    Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) is mouse-derived IgG2a κ type antibody inhibitor, targeting to influenza virus nucleoprotein. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) reacts with influenza virus nucleoprotein (NP). Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can induce passive immunity to influenza A virus. Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65)) can be used for the detections of western blot, flow cytometry and immunohistochemistry in Influenza A virus infection.
    Anti-Influenza A virus NP Antibody (H16-L10-4R5 (HB-65))
  • HY-P990828
    Anti-PD-L1/B7-H1 Antibody (29E.2A3) 99%
    Anti-PD-L1/B7-H1 Antibody (29E.2A3) is a kind of mouse IgG2b κ chimeric antibody inhibitor, targeting to human PD-L1/B7-H1. Anti-PD-L1/B7-H1 Antibody (29E.2A3) can block the binding of PD-1 to PD-L1. Anti-PD-L1/B7-H1 Antibody (29E.2A3) can be used for the research of infection, such as hepatitis C virus (HCV).
    Anti-PD-L1/B7-H1 Antibody (29E.2A3)
  • HY-P991246
    VRC01LS 98.78%
    VRC01LS is a humanized monoclonal antibody inhibitor targeting the CD4-binding site of HIV-1 envelope glycoprotein (Env). VRC01LS blocks the binding of HIV-1 to host cell CD4 receptor, inhibiting viral entry. VRC01LS is promising for research of HIV-1 infection.
    VRC01LS
  • HY-P991450
    ADI-15878 99.80%
    ADI-15878 is a human IgG monoclonal antibody (mAb) targeting Envelope glycoprotein, GP2. ADI-15878 can be used in Ebola virus infection research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    ADI-15878
  • HY-W004056
    4-Methoxyphenethyl alcohol 702-23-8 99.90%
    4-Methoxyphenethyl alcohol, an aromatic alcohol, is the major component in the anise-like odour produced by Amorphophallus. 4-Methoxyphenethyl alcohol can inhibits the protein, RNA and DNA synthesis in Escherichia coli.
    4-Methoxyphenethyl alcohol
  • HY-W004296
    1-Heptadecanol 1454-85-9 99.65%
    1-Heptadecanol is a long-chain primary alcohol and antibacterial agent. 1-Heptadecanol can be isolated from Solena amplexicaulis. 1-Heptadecanol exhibits antibacterial activity against Salmonella gallinarum with a minimum inhibitory concentration (MIC) of 15.08 μg/mL. 1-Heptadecanol can be used in the research of dandruff caused by Malassezia furfur.
    1-Heptadecanol
  • HY-W014352
    trans-4-Bromocinnamaldehyde 49678-04-8 99.87%
    trans-4-Bromocinnamaldehyde (Compound 6d) is an (E)-α,β-unsaturated aldehyde and cinnamaldehyde derivative. trans-4-Bromocinnamaldehyde serves as a starting material for the synthesis of α-aryl substituted phosphinomycin analogs. trans-4-Bromocinnamaldehyde can be used in the research of tuberculosis.
    trans-4-Bromocinnamaldehyde
  • HY-W017463
    trans-3-(3-Pyridyl)acrylic acid 19337-97-4 99.87%
    trans-3-(3-Pyridyl) acrylic acid is an unsaturated carboxylic acid and synthetic building block, which serves as a synthetic precursor of 3-(3-pyridyl) propanoic acid. trans-3-(3-Pyridyl) acrylic acid can be used to prepare dual mutant IDH1/NAMPT inhibitors and PGE2 antagonist analogs. In addition, trans-3-(3-Pyridyl) acrylic acid exhibits antiviral activity against tobacco mosaic virus (TMV).
    trans-3-(3-Pyridyl)acrylic acid
  • HY-W053519
    DL-Pantolactone 79-50-5
    DL-Pantolactone is a γ-lactone that can be hydrolyzed to Pantoic acid (HY-W399035) by the lactonohydrolase of Fusarium oxysporum. DL-Pantolactone also can be used in the preparation of 3,5-dinitrobenzoyl-DL-pantolactone.
    DL-Pantolactone
  • HY-W251687
    2'-Deoxy-2'-fluoroarabinoadenosine 20227-41-2 99.92%
    2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue, which exhibits anticancer activity against human immunodeficiency virus (HIV).
    2'-Deoxy-2'-fluoroarabinoadenosine
  • HY-W506116
    Ostruthin 148-83-4 98.84%
    Ostruthin is a natural coumarin compound with bacterial and antimycobacterial activities. Ostruthin inhibits the growth of mycobacteria and Staphylococcus aureus. Ostruthin suppresses vascular smooth muscle cell proliferation as well as de novo cellular DNA synthesis. Ostruthin is applicable to research related to mycobacterial infections and cardiovascular and cerebrovascular diseases.
    Ostruthin
  • HY-W714137
    (6-Isothiocyanatohexyl)(methyl)sulfane 4430-39-1
    (6-Isothiocyanatohexyl)(methyl)sulfane (Lesquerellin; 6-Methylthiohexyl isothiocyanate) is an isothiocyanate found in wasabi (W. japonica) and has various biological activities. (6-Isothiocyanatohexyl)(methyl)sulfane is active against the bacterium Bacillus subtilis and the fungus T. mentagrophytes (MIC=25 μg/mL). (6-Isothiocyanatohexyl)(methyl)sulfane also has anthelmintic activity against blue mussel (M. edulis). (6-Isothiocyanatohexyl)(methyl)sulfane has antifouling activity when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm2 in a conventional immersion test.
    (6-Isothiocyanatohexyl)(methyl)sulfane
  • HY-128554S1
    N-Desethyl amodiaquine-d5 dihydrochloride 1216894-33-5 99.53%
    N-Desethyl amodiaquine-d5 dihydrochloride is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively.
    N-Desethyl amodiaquine-d5 dihydrochloride
  • HY-10852
    Arterolane 664338-39-0 98.0%
    Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
    Arterolane
  • HY-B0113S
    Omeprazole-d3 922731-01-9 ≥98.0%
    Omeprazole-d3 (H 16868-d3) is deuterium labeled Omeprazole. Omeprazole (H 16868) is an orally active H+,K+-ATPase inhibitor and a proton pump inhibitor. Omeprazole competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole aslo has neuroprotective and antibacterial effects.
    Omeprazole-d3
  • HY-13836
    ELQ-300 1354745-52-0 ≥98.0%
    ELQ-300 is a potent and orally bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1). ELQ-300 inhibits growth of P. falciparum Dd2, Tm90-C2B, and D1 with IC50 values of 6.6, 4.6 and 160 nM, respectively. ELQ-300 can be used for the research of antimalarial.
    ELQ-300
  • HY-16467
    Squalamine lactate 320725-47-1 98.42%
    Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
    Squalamine lactate
  • HY-19882
    BAL-30072 941285-15-0 98.03%
    BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively.
    BAL-30072
  • HY-P2292
    Omiganan, FITC labeled 98.20%
    Omiganan, FITC labeled is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines.
    Omiganan, FITC labeled
  • HY-100584
    Davercin 55224-05-0 98.0%
    Davercin (Erythromycin Cyclocarbonate), derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.
    Davercin
Cat. No. Product Name / Synonyms Application Reactivity