1. Anti-infection
  2. Parasite

Arterolane (Synonyms: OZ 277; RBx 11160)

Cat. No.: HY-10852
Handling Instructions

Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.

For research use only. We do not sell to patients.

Arterolane Chemical Structure

Arterolane Chemical Structure

CAS No. : 664338-39-0

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.

IC50 & Target

IC50: 1.1 nM (P. falciparum Ro73), 1.1 nM (P. falciparum W2)[1]

In Vitro

Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5476 mL 12.7379 mL 25.4758 mL
5 mM 0.5095 mL 2.5476 mL 5.0952 mL
10 mM 0.2548 mL 1.2738 mL 2.5476 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

392.53

Formula

C₂₂H₃₆N₂O₄

CAS No.

664338-39-0

SMILES

O=C(NCC(N)(C)C)C[[email protected]](CC1)CC[[email protected]]21OO[[email protected]]3(O2)[[email protected]]4C[[email protected]@H]5C[[email protected]](C4)C[[email protected]]3C5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Arterolane
Cat. No.:
HY-10852
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Arterolane

Cat. No.: HY-10852