(6-Isothiocyanatohexyl)(methyl)sulfane
Based on 1 Customer Validation
(6-Isothiocyanatohexyl)(methyl)sulfane (Lesquerellin; 6-Methylthiohexyl isothiocyanate) is an isothiocyanate found in wasabi (W. japonica) and has various biological activities. (6-Isothiocyanatohexyl)(methyl)sulfane is active against the bacterium Bacillus subtilis and the fungus T. mentagrophytes (MIC=25 μg/mL). (6-Isothiocyanatohexyl)(methyl)sulfane also has anthelmintic activity against blue mussel (M. edulis). (6-Isothiocyanatohexyl)(methyl)sulfane has antifouling activity when applied to polyvinyl chloride (PVC) panels at a concentration of 50 μmol/cm2 in a conventional immersion test.
For research use only. We do not sell to patients.
- Purity: 96.46%
- CAS No.: 4430-39-1
- Formula: C8H15NS2
- Molecular Weight:189.34
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| J774.1 | IC50 |
14.8 μM
Compound: 2g
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Growth inhibition of mouse J774.1 cells assessed as cell viability after 24 hrs by MTT assay
Growth inhibition of mouse J774.1 cells assessed as cell viability after 24 hrs by MTT assay
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[PMID: 19716210] |
| J774.1 | IC50 |
30.4 μM
Compound: 2g
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Antiinflammatory activity in mouse J774.1 cells assessed as inhibition of IFN-gamma and LPS-induced nitric oxide production after 20 to 24 hrs by Griess assay
Antiinflammatory activity in mouse J774.1 cells assessed as inhibition of IFN-gamma and LPS-induced nitric oxide production after 20 to 24 hrs by Griess assay
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[PMID: 19716210] |
Chemical Information
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CAS No. 4430-39-1
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Appearance Viscous Liquid
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Molecular Weight 189.34
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Formula C8H15NS2
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Color Colorless to light yellow
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SMILES
CSCCCCCCN=C=S
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Synonyms
Lesquerellin; 6-Methylthiohexyl isothiocyanate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (528.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (781 KB)
- English - EN (781 KB)
- Français - FR (781 KB)
- Deutsch - DE (781 KB)
- Norwegian - NO (781 KB)
- Español - ES (781 KB)
- Swedish - SV (781 KB)
- Italian - IT (781 KB)
- Korean - KR (781 KB)
- Portuguese - PT (781 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.2815 mL | 26.4075 mL | 52.8150 mL | 132.0376 mL |
| 5 mM | 1.0563 mL | 5.2815 mL | 10.5630 mL | 26.4075 mL | |
| 10 mM | 0.5282 mL | 2.6408 mL | 5.2815 mL | 13.2038 mL | |
| 15 mM | 0.3521 mL | 1.7605 mL | 3.5210 mL | 8.8025 mL | |
| 20 mM | 0.2641 mL | 1.3204 mL | 2.6408 mL | 6.6019 mL | |
| 25 mM | 0.2113 mL | 1.0563 mL | 2.1126 mL | 5.2815 mL | |
| 30 mM | 0.1761 mL | 0.8803 mL | 1.7605 mL | 4.4013 mL | |
| 40 mM | 0.1320 mL | 0.6602 mL | 1.3204 mL | 3.3009 mL | |
| 50 mM | 0.1056 mL | 0.5282 mL | 1.0563 mL | 2.6408 mL | |
| 60 mM | 0.0880 mL | 0.4401 mL | 0.8803 mL | 2.2006 mL | |
| 80 mM | 0.0660 mL | 0.3301 mL | 0.6602 mL | 1.6505 mL | |
| 100 mM | 0.0528 mL | 0.2641 mL | 0.5282 mL | 1.3204 mL |
(6-Isothiocyanatohexyl)(methyl)sulfane Related Classifications
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