2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-157084
    HS-291 98%
    HS-291 is a HtpG inhibitor of Borrelia burgdorferi (Bb). HS-291 contains BX-2819 (high affinity for Bb HtpG), PEG linker, and Verteporfin (HY-B0146) (a photoactive toxin).HS-291 produces reactive oxygen species under light activation to oxidize HtpG and a discrete protein subset near chaperone proteins and can quickly and irreversibly inactivate Bb.
    HS-291
  • HY-157150
    mAC2-IN-1 98%
    mAC2-IN-1 (compound 14) is a potent and selective human adenylate cyclases (mACs) inhibitor with an IC50 of 4.45 μM. mAC2-IN-1 has low activity on mAC1 and mAC5.
    mAC2-IN-1
  • HY-157172
    MorHap 98%
    MorHap is a heroin hapten. MorHap conjugated to tetanus toxoid (TT), palm-CV2, and to monophosphoryl lipid A (MPLA)-containing liposomes partially blocks heroin-induced analgesia and hyperlocomotion in mice. MorHap designed conjugates also significantly inhibits HIV-1 binding to α4β7 receptors. MorHap can be used in research to develop vaccines related to heroin addiction and HIV-1 infection.
    MorHap
  • HY-157192
    Clothianidin-2-S-propanoic acid 912270-45-2 98%
    Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide.
    Clothianidin-2-S-propanoic acid
  • HY-157249
    Antiviral agent 43 2739990-96-4 98%
    Antiviral agent 43 (compound 16) is a potent and orally active influenza A viruses entry inhibitor. Antiviral agent 43 inhibits replications of influenza A strains VH04-H5N1 and PR8-H1N1 with EC50s of 240 nM and 72 nM, respectively.
    Antiviral agent 43
  • HY-15728S
    Radotinib-d6 2754051-83-5 98%
    Radotinib-d6 is deuterium labeled Radotinib (HY-15728). Radotinib (IY-5511) is an orally active and BBB-permeable selective tyrosine kinase Bcr-Abl1 inhibitor with an IC50 of 34 nM. Radotinib has anti-prion and anti-tumor activities. Radotinib can inhibit the proliferation, induce cell cycle arrest and apoptosis of tumor cells . Radotinib can be used in the research of cancer such as chronic myeloid leukemia and multiple myeloma, as well as neurodegenerative diseases such as prion diseases.
    Radotinib-d6
  • HY-157314
    HDAC6-IN-27 2758023-91-3 98%
    HDAC6-IN-27 (compound 8C) is a HDAC inhibitor with IC50 vales of 15.9 nM 136.5 nM and 6180.2 nM for HDAC6, HDAC8 and HDAC1, respectively. HDAC6-IN-27 shows potent antiparasitic effects.
    HDAC6-IN-27
  • HY-157368
    Bismuth Sulfite Agar 98%
    Bismuth Sulfite Agar is a selective solid medium that can be used for the isolation, determination and culture of Salmonella.
    Bismuth Sulfite Agar
  • HY-157375
    Brain Heart Infusion Agar 98%
    Brain Heart Infusion Agar is growth medium for the cultivation of a wide variety of microorganisms.
    Brain Heart Infusion Agar
  • HY-157377
    Yeast Peptone Dextrose Agar 98%
    Yeast Peptone Dextrose Agar (YPD Agar) is a solid medium for rapid growth of yeast.
    Yeast Peptone Dextrose Agar
  • HY-15739R
    Ansamitocin P-3 (Standard) 66584-72-3
    Ansamitocin P-3 (Standard) is the analytical standard of Ansamitocin P-3. This product is intended for research and analytical applications. Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
    Ansamitocin P-3 (Standard)
  • HY-157433
    Mab-SaS-IN-1 773869-38-8 98%
    Mab-SaS-IN-1 (compoud 1H) is Mab-SaS inhibitor with the IC50 of 2 μM. Mab-SaS-IN-1 can be used for study of antibiosis by blocking iron uptake and metabolism.
    Mab-SaS-IN-1
  • HY-157477
    SARS-CoV-2 3CLpro-IN-22 98%
    SARS-CoV-2 3CLpro-IN-22 (Compound 17) is a cathepsin L (CTSL ) inhibitor with an IC50 value of 32.5 nM. SARS-CoV-2 3CLpro-IN-22 can be used for the study of SARS-CoV-2 virus.
    SARS-CoV-2 3CLpro-IN-22
  • HY-157479
    DPI-2016 2760731-35-7 98%
    DPI-2016 is a antibacterial agent. DPI-2016 shows improved bactericidal activity (MIC, 0.25-8 μg/mL) against all bacterial strains compared to the aztreonam (HY-B0129) (MIC, 16->64 μg/mL).
    DPI-2016
  • HY-157482
    EBP-59 3033056-76-4 98%
    EBP-59 is a bacterial inhibitor with antibiofilm activity against Gram-positive bacteria. EBP-59 is effective against Staphylococcus aureus and MRSA (methicillin–resistant staphylococcus aureus). EBP-59 can be used to study bacterial infections.
    EBP-59
  • HY-157492
    RO7075573 2097284-11-0 98%
    RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections.
    RO7075573
  • HY-157550
    DENV-IN-12 2581065-80-5 98%
    DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines.
    DENV-IN-12
  • HY-157804
    PROTAC SARS-CoV-2 Mpro degrader-1 3029579-46-9 98%
    PROTAC SARS-CoV-2 Mpro degrader-1 (compound 5) is a PROTAC degrader targeting the major SARS-CoV-2 protease with broad-spectrum antiviral activity.
    PROTAC SARS-CoV-2 Mpro degrader-1
  • HY-157805
    PROTAC SARS-CoV-2 Mpro degrader-2 3057294-32-0 98%
    PROTAC SARS-CoV-2 Mpro degrader-2 (Compound 6) is a potent PROTAC degrader of SARS-CoV-2 Mpro. PROTAC SARS-CoV-2 Mpro degrader-2 has broad-spectrum antiviral activity against CoVs, including SARS-CoV-2 (EC50 = 10.8 μM), HCoV-OC43 (EC50 = 1.6 μM) and HCoV-229E (EC50 = 6.5 μM). PROTAC SARS-CoV-2 Mpro degrader-2 exhibits potent activity against SARS-CoV-2 in Calu-3 cells, with an EC50 of 0.89 μM.
    PROTAC SARS-CoV-2 Mpro degrader-2
  • HY-157808
    Antibacterial agent 185 98%
    Antibacterial agent 185 (compound IP-01) is a potent antibacterial agent. Antibacterial agent 185 inhibits filamentous temperature-sensitive mutant Z (FtsZ) polymerization and bundling by increasing GTP hydrolysis. Antibacterial agent 185 inhibits Streptococcus pneumoniae and shows narrow-spectrum activity.
    Antibacterial agent 185
Cat. No. Product Name / Synonyms Application Reactivity