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Cat. No.: HY-157479

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DPI-2016

DPI-2016 is a antibacterial agent. DPI-2016 shows improved bactericidal activity (MIC, 0.25-8 μg/mL) against all bacterial strains compared to the aztreonam (HY-B0129) (MIC, 16->64 μg/mL).

For research use only. We do not sell to patients.

CAS No.: 2760731-35-7
Formula: C₂₅H₃₂N₈O₁₀S₂
Molecular Weight:668.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

DPI-2016 Chemical Structure

CAS No.: 2760731-35-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DPI-2016 is a antibacterial agent. DPI-2016 shows improved bactericidal activity (MIC, 0.25-8 μg/mL) against all bacterial strains compared to the aztreonam (HY-B0129) (MIC, 16->64 μg/mL)^[1].

Chemical Information

CAS No. 2760731-35-7
Molecular Weight 668.70
Formula C₂₅H₃₂N₈O₁₀S₂
SMILES

OC([C@@H](O/N=C(C(N[C@H]1C(C)(C)N(OS(=O)(O)=O)C1=O)=O)/C2=C(SC(N)=N2)C)COC3=CC=C(C(N[C@@H]4CCNC4)=N)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhai L, et al. Improved synthesis and evaluation of preclinical pharmacodynamic parameters of a new monocyclic β-lactam DPI-2016. Bioorg Med Chem Lett. 2024 Jan 8:129615. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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