2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N17346
    Neoaspidistrin 163633-27-0
    Neoaspidistrin is a spirostanol saponin that can be found in the rhizomes of Aspidistra typica. Neoaspidistrin exhibits activity against HIV-1 by inhibiting viral replication. Neoaspidistrin can be used for the research of HIV-1 infection.
    Neoaspidistrin
  • HY-N17354
    Glycocitrine II 28333-13-3 98%
    Glycocitrine II is an acridone alkaloid. Glycocitrine II can be isolated from the Rutaceous plants. Glycocitrine II inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced EBV-EA activation.
    Glycocitrine II
  • HY-N17375
    Saikosaponin bk1 110352-77-7
    Saikosaponin bk1 is a NADPH-oxidase 5(NOX5) dehydrogenase domain binder and hepatoprotective agent. Saikosaponin bk1 forms stable interactions with the dehydrogenase domain of NOX5 from Cylindrospermum stagnale. Saikosaponin bk1 is applicable to research related to COVID-19 and alcoholic liver injury.
    Saikosaponin bk1
  • HY-N17385
    Chrysophanol dimethyl ether 71013-35-9
    Chrysophanol dimethyl ether is an anthraquinone-type natural product. Chrysophanol dimethyl ether acts as a bioavailability enhancer for antibacterial and antifungal antibiotics. Chrysophanol dimethyl ether serves as a chemical marker for differentiating raw and processed medicinal Rheum palmatum, with lower signal intensity detected in raw samples and higher signal intensity in processed samples. Chrysophanol dimethyl ether is applicable to research related to bacterial and fungal infections.
    Chrysophanol dimethyl ether
  • HY-N17390
    Citaldoxime 117091-61-9
    Citaldoxime (Compound 7) is a γ-radiation-induced antifungal stress metabolite that can be found in Citrus plants.
    Citaldoxime
  • HY-N17392
    Artoheteronin 2771017-28-6
    Artoheteronin is a prenylated coumarin found in the fruits of Artocarpus heterophyllus. Artoheteronin can inhibit HIV-1 reverse transcriptase activity with an EC50 of 0.18 μM. Artoheteronin shows anti-inflammatory activity and inhibits nitric oxide production. Artoheteronin can be used for the researches of HIV infection and inflammatory disease.
    Artoheteronin
  • HY-N17399
    Bis(2-methylheptyl) phthalate 2678-38-8
    Bis (2-methylheptyl) phthalate is an orally effective antiviral agent. Bis (2-methylheptyl) phthalate inhibits the pathogenic process of white spot syndrome virus (WSSV) in Penaeus monodon. Bis (2-methylheptyl) phthalate can be used in studies related to white spot syndrome.
    Bis(2-methylheptyl) phthalate
  • HY-N17413
    (-)-γ-Cuparenol 1357469-94-3
    (-)-γ-Cuparenol is a sesquiterpene compound with an IC50 of 23.6 μg/mL against porcine Na+/K+-ATPase. (-)-γ-Cuparenol reduces phytohemagglutinin (PHA)-induced activation of NF-AT and NF-κB in Jurkat cells. (-)-γ-Cuparenol inhibits the growth of Gram-positive bacteria and some Gram-negative bacteria. (-)-γ-Cuparenol exhibits weak inhibitory activity against Candida albicans. (-)-γ-Cuparenol is applicable for research related to immunoregulation, cardiovascular diseases and bacterial infections.
    (-)-γ-Cuparenol
  • HY-N17440
    2-Methoxyjuglone 15127-94-3
    2-Methoxyjuglone, a naphthoquinone, is an apoptosis inducer. 2-Methoxyjuglone activates caspase-9 and caspase-3 via the mitochondrial cytochrome c-dependent intrinsic apoptosis cascade. 2-Methoxyjuglone increases pro-apoptotic Bax levels, decreases anti-apoptotic Bcl-2 levels, and promotes mitochondrial cytochrome c release. 2-Methoxyjuglone induces apoptosis morphological features, early apoptosis, S-phase and G2/M-phase cell cycle arrest, and DNA double-strand breaks. 2-Methoxyjuglone exerts activity against Gram-positive bacteria, pathogenic fungi, and phytopathogenic fungi. 2-Methoxyjuglone can be used for the research of hepatocellular carcinoma, osteosarcoma, colon adenocarcinoma, breast cancer, fungal infection, bacterial infection.
    2-Methoxyjuglone
  • HY-N17442
    Echinoside A 75410-53-6 98%
    Echinoside A is a saponin. Echinoside A can be isolated from sea cucumber. Echinoside A inhibits the catalytic activity of Top2α, reduces the noncovalent binding of Top2α to DNA. Echinoside A activates Caspase-3 and induces PARP cleavage. Echinoside A induces Apoptosis. Echinoside A has anticancer activity against prostate cancer, hepatocellular carcinoma, and S-180 sarcoma. Echinoside A exhibits antifungal activity against a variety of fungi, with a minimum growth inhibitory concentration range of 3.12 to 50.0 μg/mL, including potent activity against Aspergillus and Penicillium species.
    Echinoside A
  • HY-N17457
    N-Demethyl-N-formyldehydronuciferine 111017-06-2
    N-Demethyl-N-formyldehydronuciferine is a dehydroaporphine alkaloid. N-Demethyl-N-formyldehydronuciferine induces mutations in Salmonella typhimurium TA98 and TA100.
    N-Demethyl-N-formyldehydronuciferine
  • HY-N17503
    Medicagenic acid 3-O-glucoside 49792-23-6 98%
    Medicagenic acid 3-O-glucoside is a monosaccharide-chain triterpenoid saponin antifungal agent that can be isolated from the roots of Medicago sativa. Against Pyricularia oryzae, Medicagenic acid 3-O-glucoside has a MIC of 0.03 mg/mL and a MFC of 0.125 mg/mL. Medicagenic acid 3-O-glucoside alters the permeability of fungal cell membranes, causing cell rupture and inhibiting fungal growth. Medicagenic acid 3-O-glucoside can be used in studies related to rice blast.
    Medicagenic acid 3-O-glucoside
  • HY-N17527
    7-Demethoxytylophorine N-oxide 128922-80-5
    7-Demethoxytylophorine N-oxide is an alkaloid inhibitor of Tobacco Mosaic Virus. 7-Demethoxytylophorine N-oxide can be isolated from the aerial parts of Cynanchum komarovii. 7-Demethoxytylophorine N-oxide is applicable to research related to Tobacco Mosaic Virus infection.
    7-Demethoxytylophorine N-oxide
  • HY-N17533
    Sargentodoside D 1868129-15-0
    Sargentodoside D is a phenolic glycoside. Sargentodoside D occurs in the stems of Sargentodoxa cuneata. Sargentodoside D is applicable to research on infections caused by Acinetobacter baumannii, Candida albicans and Staphylococcus aureus, as well as research on cervical cancer.
    Sargentodoside D
  • HY-N17550
    25-Hydroperoxycycloart-23-en-3β-ol 173740-54-0 98%
    25-Hydroperoxycycloart-23-en-3β-ol is an anticancer, antibacterial, and antimalarial agent. 25-Hydroperoxycycloart-23-en-3β-ol can be isolated from Blepharodon nitidum. 25-Hydroperoxycycloart-23-en-3β-ol exhibits anti-Mycobacterium tuberculosis and antileishmanial activities. 25-Hydroperoxycycloart-23-en-3β-ol shows significant cytotoxic activity against a panel of tumor cell lines (large cell lung cancer, melanoma, colon adenocarcinoma, chronic myelogenous leukemia).
    25-Hydroperoxycycloart-23-en-3β-ol
  • HY-N17557
    Schizanrin D 343326-65-8 98%
    Schizanrin D (Schizarin D) is a C18 Dibenzocyclooctadiene lignin. Schizanrin D can be derived from dried stems of Kadsura matsudai. Schizanrin D inhibits HBeAg production. Schizanrin D is inactive in vitro against HIV replication.
    Schizanrin D
  • HY-N17566
    Eukovoside 83475-36-9
    Eukovoside is a cinnamic acid derivative found in Euphrasia regelii with anti-inflammatory, antioxidant, antibacterial, antiallergic, and antihistamine activity. Eukovoside can be used for the research of hyperglycemic diseases, eye inflammation, upper respiratory passages inflammation, hay fever, conjunctivitis, colds, influenza, sinusitis.
    Eukovoside
  • HY-N17582
    (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside 1526987-82-5
    (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside is a Streptococcus mutans Sortase A inhibitor with an IC50 of 37.3 μM. (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside inhibits transpeptidase activity linked to Gram-positive bacterial surface protein anchoring. (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside can be used for the research of dental caries.
    (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside
  • HY-N17584
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside 126371-34-4
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside (compound 1) is a lignan found in the dried roots of Pulsatilla koreana and Sortase A inhibitor with an IC50 of 67.7 μM against Streptococcus mutans OMZ65 Sortase A. (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside can be used for the research of dental caries.
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside
  • HY-N17621
    Chinenol A 633294-59-4 98%
    Chinenol A is an antibacterial agent that can be found in the aerial part of Helwingia chinensis. Chinenol A can be used for the research of bacterial infections (staphylococcus aureus infection, mycobacterium tuberculosis infection, streptococcus pneumonia infection).
    Chinenol A
Cat. No. Product Name / Synonyms Application Reactivity