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  3. 25-Hydroperoxycycloart-23-en-3β-ol

25-Hydroperoxycycloart-23-en-3β-ol is an anticancer, antibacterial, and antimalarial agent. 25-Hydroperoxycycloart-23-en-3β-ol can be isolated from Blepharodon nitidum. 25-Hydroperoxycycloart-23-en-3β-ol exhibits anti-Mycobacterium tuberculosis and antileishmanial activities. 25-Hydroperoxycycloart-23-en-3β-ol shows significant cytotoxic activity against a panel of tumor cell lines (large cell lung cancer, melanoma, colon adenocarcinoma, chronic myelogenous leukemia).

For research use only. We do not sell to patients.

25-Hydroperoxycycloart-23-en-3β-ol

25-Hydroperoxycycloart-23-en-3β-ol Chemical Structure

CAS No. : 173740-54-0

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Description

25-Hydroperoxycycloart-23-en-3β-ol is an anticancer, antibacterial, and antimalarial agent. 25-Hydroperoxycycloart-23-en-3β-ol can be isolated from Blepharodon nitidum. 25-Hydroperoxycycloart-23-en-3β-ol exhibits anti-Mycobacterium tuberculosis and antileishmanial activities. 25-Hydroperoxycycloart-23-en-3β-ol shows significant cytotoxic activity against a panel of tumor cell lines (large cell lung cancer, melanoma, colon adenocarcinoma, chronic myelogenous leukemia)[1].

IC50 & Target[1]

Leishmania

 

In Vitro

25-Hydroperoxycycloart-23-en-3β-ol shows moderate activity (MIC: 12.5 μg/mL) against the MDR M. tuberculosis strain[1].
25-Hydroperoxycycloart-23-en-3β-ol shows GI50 values of 30.9, 26.9, 29.9, 29.9 μg/mL for H460, M-14, HT-29, K562 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

458.72

Formula

C30H50O3

CAS No.
SMILES

CC1(C)[C@@H](O)CC[C@]2(C3)[C@]43CC[C@]5(C)[C@@H]([C@H](C)C/C=C/C(C)(OO)C)CC[C@](C)5[C@]4([H])CC[C@@]12[H]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
25-Hydroperoxycycloart-23-en-3β-ol
Cat. No.:
HY-N17550
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