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Cat. No.: HY-N17503

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Medicagenic acid 3-O-glucoside

Medicagenic acid 3-O-glucoside is a monosaccharide-chain triterpenoid saponin antifungal agent that can be isolated from the roots of Medicago sativa. Against Pyricularia oryzae, Medicagenic acid 3-O-glucoside has a MIC of 0.03 mg/mL and a MFC of 0.125 mg/mL. Medicagenic acid 3-O-glucoside alters the permeability of fungal cell membranes, causing cell rupture and inhibiting fungal growth. Medicagenic acid 3-O-glucoside can be used in studies related to rice blast.

For research use only. We do not sell to patients.

CAS No.: 49792-23-6
Formula: C₃₆H₅₆O₁₁
Molecular Weight:664.82

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Medicagenic acid 3-O-glucoside Chemical Structure

CAS No.: 49792-23-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Medicagenic acid 3-O-glucoside (0.03-0.125 mg/mL; 7 h-10 d) strongly inhibits growth of Pyricularia oryzae isolates in vitro, with a MIC of 0.03 mg/mL and MFC of 0.125 mg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

Pyricularia oryzae
Concentration:

0.50, 0.25, 0.125, 0.06, 0.03, 0.015, and 0.0075 mg/mL
Incubation Time:

10 days; changed fresh cultural medium at 24 h intervals.
Result:

Inhibited the growth of Pyricularia oryzae isolates in vitro, with a MIC of 0.03 mg/mL and MFC of 0.125 mg/mL.

Chemical Information

CAS No. 49792-23-6
Molecular Weight 664.82
Formula C₃₆H₅₆O₁₁
SMILES

C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])CC(C)(CC4)C)C(O)=O)C)([H])[C@@]5([C@@]([C@@](C)([C@H]([C@H](C5)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C(O)=O)([H])CC1)C
Structure Classification
- Terpenoids
- Triterpenes
- Terpenoids
- Pentacyclic Triterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Abbruscato P, et al. Triterpenoid glycosides from Medicago sativa as antifungal agents against Pyricularia oryzae. J Agric Food Chem. 2014;62(46):11030-11036. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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