2. Anti-infection
  3. Fungal
  4. Medicagenic acid 3-O-glucoside

Medicagenic acid 3-O-glucoside is a monosaccharide-chain triterpenoid saponin antifungal agent that can be isolated from the roots of Medicago sativa. Against Pyricularia oryzae, Medicagenic acid 3-O-glucoside has a MIC of 0.03 mg/mL and a MFC of 0.125 mg/mL. Medicagenic acid 3-O-glucoside alters the permeability of fungal cell membranes, causing cell rupture and inhibiting fungal growth. Medicagenic acid 3-O-glucoside can be used in studies related to rice blast.

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Medicagenic acid 3-O-glucoside

Medicagenic acid 3-O-glucoside Chemical Structure

CAS No. : 49792-23-6

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Medicagenic acid 3-O-glucoside Related Antibodies

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Description

Medicagenic acid 3-O-glucoside is a monosaccharide-chain triterpenoid saponin antifungal agent that can be isolated from the roots of Medicago sativa. Against Pyricularia oryzae, Medicagenic acid 3-O-glucoside has a MIC of 0.03 mg/mL and a MFC of 0.125 mg/mL. Medicagenic acid 3-O-glucoside alters the permeability of fungal cell membranes, causing cell rupture and inhibiting fungal growth. Medicagenic acid 3-O-glucoside can be used in studies related to rice blast[1].

In Vitro

Medicagenic acid 3-O-glucoside (0.03-0.125 mg/mL; 7 h-10 d) strongly inhibits growth of Pyricularia oryzae isolates in vitro, with a MIC of 0.03 mg/mL and MFC of 0.125 mg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Medicagenic acid 3-O-glucoside Related Antibodies

Cell Viability Assay[1]

Cell Line: Pyricularia oryzae
Concentration: 0.50, 0.25, 0.125, 0.06, 0.03, 0.015, and 0.0075 mg/mL
Incubation Time: 10 days; changed fresh cultural medium at 24 h intervals.
Result: Inhibited the growth of Pyricularia oryzae isolates in vitro, with a MIC of 0.03 mg/mL and MFC of 0.125 mg/mL.
Molecular Weight

664.82

Formula

C36H56O11
CAS No.
SMILES

C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])CC(C)(CC4)C)C(O)=O)C)([H])[C@@]5([C@@]([C@@](C)([C@H]([C@H](C5)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C(O)=O)([H])CC1)C
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
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Medicagenic acid 3-O-glucoside Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Medicagenic acid 3-O-glucoside49792-23-6FungalMedicago sativaPyricularia oryzaefungal growthrice blastfungal cell membrane permeabilityInhibitorinhibitorinhibit

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