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Cat. No.: HY-N17557

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Schizanrin D

(Synonyms: Schizarin D)

Schizanrin D (Schizarin D) is a C₁₈ Dibenzocyclooctadiene lignin. Schizanrin D can be derived from dried stems of Kadsura matsudai. Schizanrin D inhibits HBeAg production. Schizanrin D is inactive in vitro against HIV replication.

For research use only. We do not sell to patients.

CAS No.: 343326-65-8
Formula: C₂₇H₃₂O₈
Molecular Weight:484.54

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

Schizanrin D Chemical Structure

CAS No.: 343326-65-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

All HIV Isoforms :

In Vitro

Schizanrin D (10-20 μg/mL; 3 days) inhibits HBeAg production in MS-G2 cells at 10 μg/mL (20.6 μM) with a 25.8% decrease but is cytotoxic at 20 μg/mL (41.3 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay^[1]

Cell Line:

MS-G2 cells (HBV DNA-integrated hepatoblastoma-derived cell line)
Concentration:

10 μg/mL (20.6 μM); 20 μg/mL (41.3 μM)
Incubation Time:

3 days
Result:

Inhibited HBeAg production with a 25.8% decrease at 10 μg/mL (20.6 μM); Caused cytotoxicity with an AST value of 47.8 IU/L (indicating cell damage) at 20 μg/mL (41.3 μM).

Chemical Information

CAS No. 343326-65-8
Molecular Weight 484.54
Formula C₂₇H₃₂O₈
SMILES

C/C=C(C)/C(O[C@H]1[C@H](C)[C@H](C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3O)=O
Synonyms

Schizarin D
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kuo YH, et al. Schizanrins [corrected] B, C, D, and E, four new lignans from Kadsura matsudai and their antihepatitis activities. J Nat Prod. 2001 Apr;64(4):487-90. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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