2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2178
    Saikosaponin F 62687-63-2 99.90%
    Saikosaponin F is a component found in Bupleurum (B.) falcatum L.
    Saikosaponin F
  • HY-N2191
    Ecliptasaponin D 206756-04-9 99.28%
    Ecliptasaponin D is a triterpenoid glucoside isolated from Eclipta alba (L.) Hassk which is the aerial part of Eclipta prostrate. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant and immunomodulatory[1,2].
    Ecliptasaponin D
  • HY-N2505
    Iristectorigenin A 39012-01-6 99.65%
    Iristectorigenin A is a natural isoflavone isolated from B. chinensis rhizomes. Iristectorigenin A shows antioxidant activity.
    Iristectorigenin A
  • HY-N3243
    Moracin P 102841-46-3 ≥99.0%
    Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects.
    Moracin P
  • HY-N4073
    6"-O-Malonyldaidzin 124590-31-4 98.35%
    6"-O-Malonyldaidzin is a malonylated isoflavone isolated from soybean seeds. 6"-O-Malonyldaidzin may has protective effect on eye.
    6
  • HY-N4107
    Phyllanthin 10351-88-9 99.97%
    Phyllanthin is an effective oral anticancer agent. Phyllanthin inhibits MOLT-4 cell viability, increases apoptosis, inhibits cell migration and invasion. Phyllanthin exerts anti-fibrotic effects by down-regulating TGF signaling pathway via ALK5 and Smad2/3. Phyllanthin also has anti-inflammatory and antibacterial properties .
    Phyllanthin
  • HY-N4134
    Ciwujianoside C3 114906-74-0 99.65%
    Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.
    Ciwujianoside C3
  • HY-N4233
    Bisabolangelone 30557-81-4 98.94%
    Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities.
    Bisabolangelone
  • HY-N4244
    Kakkalide 58274-56-9 99.80%
    Kakkalide is an isoflavone derived from the flowers of Pueraria lobata. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species (ROS)-associated inflammation.
    Kakkalide
  • HY-N5124
    Meloside A 60767-80-8 98.72%
    Meloside A (Isovitexin 2''-O-glucoside) is a flavonoid with antioxidant activity. Meloside A can inhibit cell apoptosis and ROS production. Meloside A can inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Meloside A can reduce IL-6, TGF-β1 and DKK-1 levels. Meloside A can be used for the researches of inflammation and endocrinology, such as hair loss.
    Meloside A
  • HY-N6020
    (-)-Butin 492-14-8 99.57%
    (-)-Butin is a enantiomer of Butin (HY-N6020B). Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities.
    (-)-Butin
  • HY-N6071
    Secoisolariciresinol 29388-59-8 99.00%
    Secoisolariciresinol ((-)-Secoisolariciresinol) is a plant lignan and a precursor of enterolignans. Secoisolariciresinol can be converted into enterodiol and enterolactone by intestinal microflora. Secoisolariciresinol may reduce the risk of cancer and cardiovascular diseases.
    Secoisolariciresinol
  • HY-N6641
    Monascin 21516-68-7 99.79%
    Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist.
    Monascin
  • HY-N6895
    Violanthin 40581-17-7 98.27%
    Violanthin is isolated from the stems of Dendrobium officinale, has potent antioxidant and antibacterial activities. Violanthin inhibits acetylcholinesterase (AChE) with an IC50 value of 79.80 μM.
    Violanthin
  • HY-N7627
    Regaloside C 117591-85-2 99.62%
    Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. Regaloside C targets multiple molecules including TNF-α, MMP-2, ERα, AKT1, TLR4 and HSP90-α. Regaloside C is applicable to research related to inflammatory diseases.
    Regaloside C
  • HY-N7976
    Quercetin 3-O-neohesperidoside 32453-36-4 99.79%
    Quercetin 3-O-neohesperidoside is a flavonol diglycoside with NO production inhibitory activity and anti-inflammatory activity. Quercetin 3-O-neohesperidoside targets activated macrophages to block NO production, with an IC50 of 55 μM. Quercetin 3-O-neohesperidoside can be used in the research of inflammatory diseases.
    Quercetin 3-O-neohesperidoside
  • HY-N8343
    Arjunglucoside I 62319-70-4 99.77%
    Arjunglucoside I, a natural compound, possesses antimicrobial activity with a MIC of 1.9 μg/mL.
    Arjunglucoside I
  • HY-N8407
    Carminic acid 1260-17-9
    Carminic acid is a widely used and orally active natural red pigment that can be used in industries such as food, cosmetics, and pharmaceuticals. In addition, carminic acid has anti-inflammatory and antioxidant activities.
    Carminic acid
  • HY-N9366
    Tumulosic acid 508-24-7 98.66%
    Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM.
    Tumulosic acid
  • HY-P1190
    c-JUN peptide 610273-01-3 99.60%
    c-JUN peptide is a cell-permeable c-JUN-JNK interaction inhibitor. c-JUN peptide inhibits serum-induced c-Jun phosphorylation. c-JUN peptide induces apoptosis.
    c-JUN peptide
Cat. No. Product Name / Synonyms Application Reactivity