1. Metabolic Enzyme/Protease
    NF-κB
    Immunology/Inflammation
  2. HIF/HIF Prolyl-Hydroxylase
    Reactive Oxygen Species
  3. Moracin P

Moracin P 

Cat. No.: HY-N3243
Handling Instructions

Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects.

For research use only. We do not sell to patients.

Moracin P Chemical Structure

Moracin P Chemical Structure

CAS No. : 102841-46-3

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Description

Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3].

In Vitro

Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

326.34

Formula

C₁₉H₁₈O₅

CAS No.
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Moracin P
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