1. Immunology/Inflammation
  2. NO Synthase
  3. Ciwujianoside C3

Ciwujianoside C3 

Cat. No.: HY-N4134 Purity: >98.0%
Handling Instructions

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.

For research use only. We do not sell to patients.

Ciwujianoside C3 Chemical Structure

Ciwujianoside C3 Chemical Structure

CAS No. : 114906-74-0

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 2284 In-stock
Estimated Time of Arrival: December 31
5 mg USD 980 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory[1][2].

In Vitro

Cell Viability Assay[1]

Cell Line: RAW 264.7 cells
Concentration: 10 µM, 20 µM and 40 µM
Incubation Time: 24 hours
Result: Has no effect on cell cytotoxicity and inhibits NO production

Western Blot Analysis[1]

Cell Line: RAW 264.7 cells
Concentration: 10 µM, 20 µM and 40 µM
Incubation Time: 24 hours
Result: Decreases p-ERK and p-JNK expression.

RT-PCR[1]

Cell Line: RAW 264.7 cells
Concentration: 10 µM, 20 µM and 40 µM
Incubation Time: 24 hours
Result: Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.
In Vivo
Animal Model: Mice[1]
Dosage: 0.5 mg/kg
Administration: Oral administration; 0.5 mg/kg/day; 17 days
Result: Reinforced object recognition memory.
Molecular Weight

1059.24

Formula

C₅₃H₈₆O₂₁

CAS No.

114906-74-0

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

Ciwujianoside C3Ciwujianoside C 3Ciwujianoside C-3NO SynthaseNitric oxide synthasesNOSanti-inflammatoryBBB recognitionmemorybrainpenetrationInhibitorinhibitorinhibit

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Ciwujianoside C3
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HY-N4134
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