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Sapropterin dihydrochloride (Synonyms: 6R-BH4 dihydrochloride; 6R-Tetrahydro-L-biopterin dihydrochloride)

Cat. No.: HY-A0124A Purity: >98.0%
Data Sheet SDS Handling Instructions

Sapropterin dihydrochloride is a synthetic form of BH4 that is approved for the treatment of BH4 responsive PKU.

For research use only. We do not sell to patients.
Sapropterin dihydrochloride Chemical Structure

Sapropterin dihydrochloride Chemical Structure

CAS No. : 69056-38-8

Size Price Stock Quantity
10 mM * 1 mL in Water $55 In-stock
10 mg $50 In-stock
50 mg $80 In-stock
100 mg $140 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

Sapropterin dihydrochloride is a synthetic form of BH4 that is approved for the treatment of BH4 responsive PKU. (1) Sapropterin dihydrochloride can stimulate TH and TPH activities leading to improved dopamine and serotonin synthesis despite persistently elevated brain phenylalanine. (2) Sapropterin dihydrochloride is used to lower blood phenylalanine levels in tetrahydrobiopterin-responsive phenylketonuria in conjunction with a phenylalanine-restricted diet.

References
M.Wt

314.17

Formula

C₉H₁₇Cl₂N₅O₃

CAS No.

69056-38-8

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: ≥ 34 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Sapropterin dihydrochloride
Cat. No.:
HY-A0124A
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