1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-182267
    Antibiofilm agent-20
    Inhibitor
    Antibiofilm agent-20 is an orally active Escherichia coli biofilm inhibitor (IC50 = 5.5 μg/mL) and show low antibacterial activity (MIC >128 μg/mL). Antibiofilm agent-20 exhibits high lipophilicity and low solubility, resulting in low colon delivery rate. Antibiofilm agent-20 demonstrates anti-inflammatory and reduces IL-17 and TNF-α levels. Antibiofilm agent-20 can be used for the research of inflammatory bowel disease.
    Antibiofilm agent-20
  • HY-B1781A
    Sulfachloropyridazine sodium
    Inhibitor 99.34%
    Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth.
    Sulfachloropyridazine sodium
  • HY-14988
    I-A09
    Inhibitor
    I-A09 and its derivatives, specifically 1,2,3-triazole-adamantylacetamide hybrids (5a–u), exhibit significant antitubercular activity. These hybrids were synthesized using copper-catalyzed click chemistry, combining bioactive fragments from antitubercular I-A09 and substituted adamantyl urea. The compound N-(1-adamantyl)-2-azido acetamide was reacted with various alkyl/aryl acetylenes to produce new analogues. Among them, N-(1-adamantan-1-yl)-2-(4-(phenanthren-2-yl)-1H-1,2,3-triazol-1-yl)acetamide (5t) showed the most promise with a minimum inhibitory concentration (MIC) of 3.12 μg/mL against Mycobacterium tuberculosis H37Rv, and a selectivity index greater than 15.
    I-A09
  • HY-146449
    PXYD4
    Inhibitor
    PXYD4 is a ribosomal protein S1 (RpsA) antagonist with Kds of 3.24 and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb).
    PXYD4
  • HY-N6739R
    Beauvericin (Standard)
    Inhibitor
    Doxycycline (monohydrate) (Standard) is the analytical standard of Doxycycline (monohydrate). This product is intended for research and analytical applications. Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor.
    Beauvericin (Standard)
  • HY-N2388R
    Auraptene (Standard)
    Inhibitor
    Auraptene (Standard) is the analytical standard of Auraptene. This product is intended for research and analytical applications. Auraptene is an orally active geranyloxycoumarin that can be isolated from plants in the Brassicaceae family, antibacterial, anti-pathogen, antioxidant, anti-tumor, and neuroprotective effects. Auraptene plays an important role in the treatment of various chronic diseases such as hypertension and cystic fibrosis.
    Auraptene (Standard)
  • HY-16742R
    Gepotidacin (Standard)
    Inhibitor
    Gepotidacin (Standard) is the analytical standard of Gepotidacin. This product is intended for research and analytical applications. Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor.
    Gepotidacin (Standard)
  • HY-145874
    Antibacterial agent 76
    Inhibitor
    Antibacterial agent 76 (compound 9) is an antibacterial agent.
    Antibacterial agent 76
  • HY-N12421
    Paulomycin A
    Inhibitor
    Paulomycin A (Volonomycin A) has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics.
    Paulomycin A
  • HY-146373
    Antibacterial agent 95
    Inhibitor
    The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.
    Antibacterial agent 95
  • HY-119669
    Furylfuramide
    Inhibitor
    Furylfuramide is a food preservative that exhibits mutagenic activity. Furylfuramide can be degraded through the aerobic metabolism by liver microsomes.
    Furylfuramide
  • HY-182033
    ClpP agonist 1
    Inhibitor
    ClpP agonist 1 is a Staphylococcus aureus ClpP (SaClpP) agonist with an EC50 of 1.44 μM, Kd values of 2.95 μM (isothermal titration calorimetry) and 18 μM (bio-layer interferometry), and a low drug resistance frequency. ClpP agonist 1 reduces bacterial load, shrinks infected area and improves histopathological outcomes in a mouse skin infection model. ClpP agonist 1 can be used for the research of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) skin infections.
    ClpP agonist 1
  • HY-N10302
    Bipolamine G
    Inhibitor
    Bipolamine G is an antibacterial polyketide alkaloid.
    Bipolamine G
  • HY-P2070
    Aspartocin D
    Inhibitor
    Aspartocin D is an analogue of Amphomycin (HY-P3078). Aspartocin D shows antimicrobial activities against Gram-positive bacteria.
    Aspartocin D
  • HY-N19935
    Mammea B/BA
    Inhibitor
    Mammea B/BA is a bacteriostatic agent found in the seeds of Mammea americana L. Mammea B/BA inhibits growth of Staphylococcus aureus strains. Mammea B/BA can be used for the research of methicillin-resistant Staphylococcus aureus infection.
    Mammea B/BA
  • HY-183275
    Antibacterial agent 340
    Inhibitor
    Antibacterial agent 340 is a DNA gyrase inhibitor. Antibacterial agent 340 exhibits broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Antibacterial agent 340 disrupts bacterial cell membrane integrity, induces reactive oxygen species (ROS) accumulation, and inhibits and eradicates bacterial biofilms. Antibacterial agent 340 can be used for the research of bacterial infections.
    Antibacterial agent 340
  • HY-12485R
    TBA-354 (Standard)
    Inhibitor
    Polyphyllin VI (Standard) is the analytical standard of Polyphyllin VI. This product is intended for research and analytical applications. Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer.
    TBA-354 (Standard)
  • HY-P5605
    Maximin 2
    Inhibitor
    Maximin 2 is an antimicrobial peptide derived from skin secretions of Bombina maxima. Maximin 2 has cytotoxicity on tumor cells and spermicidal effect.
    Maximin 2
  • HY-115442
    NHNB
    Inhibitor
    NHNB is a selective HDAC8 inhibitor (IC50 = 66.0 μM) and Peptidoglycan N-acetylglucosamine (GlcNAc) deacetylases (PGNGdacs) inhibitor. NHNB shows antibacterial and bactericidal activity against B. anthracis and B. cereus. NHNB can be used for the research of acute myeloid leukemia, Bacillus anthracis infection, and Bacillus cereus infection.
    NHNB
  • HY-119945
    Brobactam
    Inhibitor
    Brobactam is a potent synthetic wide spectrum β-lactamase inhibitor. Brobactam has antibacterial activity.
    Brobactam
Cat. No. Product Name / Synonyms Application Reactivity