Antibacterial agent 95
The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.
For research use only. We do not sell to patients.
- CAS No.: 2413006-48-9
- Formula: C19H16ClNO3
- Molecular Weight:341.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>20 μM
Compound: 3h
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 32113048] |
| HepG2 | CC50 |
>20 μM
Compound: 3h
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
|
[PMID: 32113048] |
| Vero | CC50 |
>20 μM
Compound: 3h
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 32113048] |
| Vero | CC50 |
>20 μM
Compound: 3h
|
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
|
[PMID: 32113048] |
Chemical Information
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CAS No. 2413006-48-9
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Molecular Weight 341.79
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Formula C19H16ClNO3
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SMILES
COC1=CC2=C(N=C(C=C2OCC(C3=CC=CC(Cl)=C3)=O)C)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 95 Related Classifications
HY-146373 Related Classifications
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