1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Stem Cell/Wnt
  3. Casein Kinase
  4. CK2 Isoform
  5. CK2 Inhibitor

CK2 Inhibitor

CK2 Inhibitors (25):

Cat. No. Product Name Effect Purity
  • HY-50855
    Silmitasertib
    Inhibitor 99.92%
    Silmitasertib (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'.
  • HY-14393
    Emodin
    Inhibitor 99.20%
    Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound.
  • HY-B0183
    Ellagic acid
    Inhibitor ≥98.0%
    Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.
  • HY-14394
    TBB
    Inhibitor 99.31%
    TBB is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.
  • HY-50855B
    Silmitasertib sodium salt
    Inhibitor 99.91%
    Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'.
  • HY-15535
    DMAT
    Inhibitor 98.09%
    DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.
  • HY-15479
    TTP 22
    Inhibitor 98.03%
    TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.
  • HY-119751
    Hematein
    Inhibitor
    Hematein is a oxidation product of hematoxylin acted as a dye.
  • HY-129571
    BioE-1115
    Inhibitor 98.08%
    BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM.
  • HY-139004
    SGC-CK2-1
    Inhibitor 99.41%
    SGC-CK2-1 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC50s of 36 and 16 nM for CK2α and CK2α′respectively in the nanoBRET assay.
  • HY-135906
    CK2/ERK8-IN-1
    Inhibitor ≥99.0%
    CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 µM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 μM.
  • HY-108606
    PI-828
    Inhibitor 99.09%
    PI-828 is a dual PI3K and casein kinase 2 (CK2) inhibitor with IC50s of 173 nM, 149 nM, and 1127 nM for p110α, CK2, and CK2α2 in lipid kinase assay, respectively.
  • HY-110052
    TBCA
    Inhibitor 99.60%
    TBCA is a highly selective CK2 (casein kinase II) inhibitor with an IC50 of 110 nM and a Ki of 77 nM.
  • HY-125957
    A-3 hydrochloride
    Inhibitor 99.67%
    A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases.
  • HY-132175
    CK2 inhibitor 2
    Inhibitor 98.12%
    CK2 inhibitor 2 is a potent, selective and orally active inhibitor of CK2, with an IC50 of 0.66 nM.
  • HY-10108A
    LY294002 hydrochloride
    Inhibitor
    LY294002 hydrochloride is a potent and broad-spectrum PI3K inhibitor, with IC50 values of 0.5, 0.57, and 0.97 μM for P110α, P110δ and P110β, respectively.
  • HY-145260
    BRD4/CK2-IN-1
    Inhibitor 98.62%
    BRD4/CK2-IN-1 is the first highly effective and oral active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with IC50s of 180 nM and 230 nM for BRD4 and CK2, respectively.
  • HY-151382
    CK2-IN-3
    Inhibitor
    CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’).
  • HY-B0183A
    Ellagic acid (hydrate)
    Inhibitor
    Ellagic acid hydrate is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.
  • HY-135816
    CK2/PIM1-IN-1
    Inhibitor
    CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1, with IC50s of 3.787 μM and 4.327 μM for CK2 and PIM1, respectively.