1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR Inhibitors

FGFR Inhibitors

FGFR

FGFR1

FGFR2

FGFR3

FGFR4

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

FGFR Inhibitors
Product Name FGFR FGFR1 FGFR2 FGFR3 FGFR4 Purity
Lenvatinib  
FGFR1, IC50: 46 nM
      99.74%
Nintedanib  
FGFR1, IC50: 69 nM
FGFR2, IC50: 37 nM
FGFR3, IC50: 108 nM
  99.97%
Ponatinib  
FGFR1, IC50: 2.2 nM
      99.13%
Infigratinib  
FGFR1, IC50: 0.9 nM
FGFR2, IC50: 1.4 nM
FGFR3, IC50: 1 nM
FGFR4, IC50: 60 nM
99.16%
Erdafitinib  
FGFR1, IC50: 1.2 nM
FGFR2, IC50: 2.5 nM
FGFR3, IC50: 3.0 nM
FGFR4, IC50: 5.7 nM
99.66%
PD-089828  
FGFR1, IC50: 0.15 μM
FGFR1, Ki: 0.14 μM
     
PD-161570  
FGFR1, IC50: 39.9 nM
FGFR1, Ki: 42 nM
FGFR1 autophosphorylation, IC50: 622 nM
     
AZD4547  
FGFR1, IC50: 0.2 nM
FGFR2, IC50: 2.5 nM
FGFR3, IC50: 1.8 nM
FGFR4, IC50: 165 nM
99.68%
Pemigatinib  
FGFR1, IC50: 0.4 nM
FGFR2, IC50: 0.5 nM
FGFR3, IC50: 1.2 nM
FGFR4, IC50: 30 nM
99.88%
SU 5402  
FGFR1, IC50: 30 nM
      99.39%
PD173074  
FGFR1, IC50: 25 nM
      99.55%
Nintedanib esylate  
FGFR1, IC50: 69 nM
FGFR2, IC50: 37 nM
FGFR3, IC50: 108 nM
  99.93%
Gandotinib    
FGFR2, IC50: 32 nM
FGFR3, IC50: 106 nM
  99.96%
Fisogatinib        
FGFR4, IC50: 5 nM
99.84%
Rogaratinib  
FGFR1
FGFR2
FGFR3
FGFR4
99.15%
Lucitanib  
FGFR1, IC50: 17.5 nM
FGFR2, IC50: 82.5 nM
    99.32%
Futibatinib  
FGFR1, IC50: 3.9 nM
FGFR2, IC50: 1.3 nM
wild-type FGFR2, IC50: 0.3 nM
FGFR2 V5651, IC50: 1-3 nM
FGFR2 N550H, IC50: 3.6 nM
FGFR2 E566G, IC50: 2.4 nM
FGFR3, IC50: 1.6 nM
FGFR4, IC50: 8.3 nM
98.80%
LY2874455  
FGFR1, IC50: 2.8 nM
FGFR2, IC50: 2.6 nM
FGFR3, IC50: 6.4 nM
FGFR4, IC50: 6 nM
98.06%
Dovitinib  
FGFR1, IC50: 8 nM
 
FGFR3, IC50: 9 nM
  97.18%
KW-2449  
FGFR1, IC50: 36 nM
      99.85%
Roblitinib        
FGFR4, IC50: 1.9 nM
99.33%
PRN1371  
FGFR1, IC50: 0.6 nM
FGFR2, IC50: 1.3 nM
FGFR3, IC50: 4.1 nM
FGFR4, IC50: 19.3 nM
99.72%
CH5183284  
FGFR1, IC50: 9.3 nM
FGFR2, IC50: 7.6 nM
FGFR3, IC50: 22 nM
FGFR4, IC50: 290 nM
99.73%
Pazopanib Hydrochloride  
FGFR1, IC50: 140 nM
      99.83%
BLU9931  
FGFR1, IC50: 591 nM
FGFR2, IC50: 493 nM
FGFR3, IC50: 150 nM
FGFR4, IC50: 3 nM
99.77%
PD-166866  
FGFR1, IC50: 52.4 nM
      99.97%
Alofanib    
FGFR2
    99.83%
Sulfatinib  
FGFR1
      97.97%
Derazantinib  
FGFR1, IC50: 4.5 nM
FGFR2, IC50: 1.8 nM
FGFR3, IC50: 4.5 nM
  99.18%
Ferulic acid  
FGFR1, IC50: 3.78 μM
FGFR2, IC50: 12.5 μM
    98.57%
Dovitinib lactate  
FGFR1, IC50: 8 nM
 
FGFR3, IC50: 9 nM
  99.96%
ENMD-2076  
FGFR1, IC50: 92.7 nM
FGFR2, IC50: 70.8 nM
    99.23%
CP-547632
FGFR, IC50: 9 nM
        >99.0%
TG 100801  
FGFR1, IC50: 2 nM
FGFR2, IC50: 16 nM
    98.60%
FIIN-2  
FGFR1, IC50: 3.1 nM
FGFR2, IC50: 4.3 nM
FGFR3, IC50: 27 nM
FGFR4, IC50: 45 nM
99.95%
Orantinib  
FGFR1, Ki: 1.2 μM
      98.80%
S49076  
FGFR1, IC50: 18 nM
FGFR1V561M, IC50: 23 nM
FGFR2, IC50: 17 nM
FGFR2N549H, IC50: 19 nM
FGFR3, IC50: 15 nM
  98.62%
ODM-203  
FGFR1, IC50: 11 nM
FGFR2, IC50: 16 nM
FGFR3, IC50: 6 nM
FGFR4, IC50: 35 nM
99.33%
ENMD-2076 Tartrate  
FGFR1, IC50: 92.7 nM
FGFR2, IC50: 70.8 nM
    98.59%
SSR128129E  
FGFR1, IC50: 1.9 μM
      99.65%
EOC317  
FGFR1, IC50: 6 nM
      97.65%
CP-547632 hydrochloride
FGFR, IC50: 9 nM
        98.24%
ASP5878  
FGFR1, IC50: 0.47 nM
FGFR2, IC50: 0.6 nM
FGFR3, IC50: 0.74 nM
FGFR4, IC50: 3.5 nM
99.71%
Infigratinib phosphate  
FGFR1, IC50: 0.9 nM
FGFR2, IC50: 1.4 nM
FGFR3, IC50: 1 nM
FGFR4, IC50: 60 nM
97.74%
Lenvatinib mesylate  
FGFR1, IC50: 46 nM
      98.54%
FIIN-3  
FGFR1, IC50: 13.1 nM
FGFR2, IC50: 21 nM
FGFR3, IC50: 31.4 nM
FGFR4, IC50: 35.3 nM
98.13%
Tyrosine kinase-IN-1  
FGFR1, IC50: 2 nM
      99.47%
SKLB610  
FGFR1
      99.23%