1. Signaling Pathways
  2. PROTAC
  3. Ligand for E3 Ligase
  4. Ligand for E3 Ligase Inhibitors

Ligand for E3 Ligase Inhibitors

von Hippel-Lindau (VHL)

MDM2

Cereblon

IAP

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Ligand for E3 Ligase Modulators
Product Name von Hippel-Lindau (VHL) MDM2 Cereblon IAP Purity
Lenalidomide    
Cereblon
  99.91%
Pomalidomide    
Cereblon
  99.96%
VH032
VHL
      98.48%
Thalidomide-NH-CH2-COOH    
Cereblon
  98.20%
(S,R,S)-AHPC hydrochloride
VHL
      ≥98.0%
(S,R,S)-AHPC-Me hydrochloride
VHL
      98.32%
Cereblon modulator 1    
Cereblon
  99.51%
(S,R,S)-AHPC-Me dihydrochloride
VHL
      98.39%
Thalidomide-O-COOH    
Cereblon
  99.73%
Thalidomide-5-OH    
Cereblon
  ≥98.0%
Lenalidomide hemihydrate    
Cereblon
  99.95%
VL285
VHL
      98.38%
(S,S,S)-AHPC hydrochloride
VHL
      96.27%
Nutlin carboxylic acid  
MDM2
    98.29%
Thalidomide 4-fluoride    
Cereblon
  ≥95.0%
Lenalidomide-Br    
Cereblon
  98.99%
Thalidomide-O-C8-COOH    
Cereblon
  95.30%
Thalidomide-4-OH    
Cereblon
  99.88%
VH032-cyclopropane-F
VHL
      95.47%
Thalidomide-propargyl    
Cereblon
  99.97%
Thalidomide 5-fluoride    
Cereblon
  99.03%
Lenalidomide-OH    
Cereblon
  99.48%
cIAP1 ligand 1      
cIAP1
98.51%
VHL Ligand 8
VHL
      98.12%
VH032 thiol
VHL
      95.91%
KB02-COOH    
Cereblon
  98.88%
(S,R,S)-AHPC-Boc
VHL
      95.15%
(S,R,S)-AHPC-Me
VHL
     
(S,R,S)-AHPC
VHL
     
Thalidomide-NH-PEG3-CH2CHO    
Cereblon
 
Thalidomide-O-C8-Boc    
Cereblon
  95.12%
(S,R,S)-AHPC TFA
VHL
     
(4R,5S)-Nutlin carboxylic acid  
MDM2
   
β-Naphthoflavone-CH2-Br      
cIAP1
Bestatin-amido-Me      
cIAP1
MV-1-NH-Me      
cIAP1
β-Naphthoflavone-CH2-OH      
cIAP1
cIAP1 ligand 2      
cIAP1
CRBN modulator-1    
Cereblon
 
Lenalidomide hydrochloride    
Cereblon