1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE6 Isoform

PDE6

 

PDE6 Related Products (14):

Cat. No. Product Name Effect Purity
  • HY-B0442A
    Vardenafil hydrochloride
    Inhibitor 99.48%
    Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-18252
    Avanafil
    Inhibitor ≥98.0%
    Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively.
  • HY-145319
    FPFT-2216
    Inhibitor 99.35%
    FPFT-2216, a “molecular glue” compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α).
  • HY-B0442
    Vardenafil
    Inhibitor 99.58%
    Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-145321
    TMX-4100
    Inhibitor 98.42%
    TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader.
  • HY-116808B
    TPN729MA
    Inhibitor
    TPN729MA (TPN729 maleate) is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM.
  • HY-116808
    TPN729
    Inhibitor
    TPN729 is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM.
  • HY-108436
    Deltazinone 1
    Inhibitor
    Deltazinone 1, a pyrazolopyridazinone, is a highly selective PDEδ inhibitor with a KD of 8 nM.
  • HY-145320
    TMX-4113
    Inhibitor 98.66%
    TMX-4113 is a degrader of phosphodiesterase 6D (PDE6D) and casein kinase 1α (CK1α).
  • HY-B0442C
    Vardenafil dihydrochloride
    Inhibitor
    Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-18252A
    Avanafil dibenzenesulfonate
    Inhibitor
    Avanafil (TA-1790) dibenzenesulfonate is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively.
  • HY-112704
    PDE5-IN-2
    Inhibitor
    PDE5-IN-2 is a potent, highly selective, and orally active PDE5 inhibitor, with an IC50 of 0.31 nM, less potently inhibits PDE2A, PDE10A, PDE4D2, and PDE6C, with IC50s of 106, 46, 43, 1.2 nM, respectively.
  • HY-B0442B
    Vardenafil hydrochloride trihydrate
    Inhibitor
    Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM.
  • HY-105349
    T-0156
    Inhibitor
    T-0156 is a potent and selective phosphodiesterase type 5 (PDE5) inhibitor.