1. Signaling Pathways
  2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Toll-like Receptor (TLR) Inhibitors

Toll-like Receptor (TLR) Inhibitors

TLR3

TLR8

TLR9

TLR2

TLR4

TLR7

TLR1

TLR6

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Toll-like Receptor (TLR) Inhibitors, Agonists & Antagonists
Product Name TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6 Purity
Resatorvid        
TLR4
      99.95%
MMG-11 quarterhydrate      
TLR2
        >97.0%
C29      
TLR2
        >98.0%
Imiquimod          
TLR7
    99.96%
CU-CPT-8m  
TLR8, IC50: 67 nM
            99.98%
Selgantolimod  
TLR8
            99.17%
CU-CPT-9a  
TLR8, IC50: 0.5 nM
            99.66%
CU-T12-9      
TLR2, EC50: 52.9 nM (in HEK-Blue cells)
   
TLR1, EC50: 52.9 nM (in HEK-Blue cells)
  99.94%
Gardiquimod diTFA  
TLR8
     
TLR7
    99.77%
IAXO-102        
TLR4
      >98.0%
Imiquimod hydrochloride          
TLR7
    99.80%
DSR-6434          
TLR7, EC50: 7.2 nM (Human)
TLR7, EC50: 4.6 nM (Mice)
    99.49%
CU-CPT9b  
TLR8, IC50: 0.7 nM
TLR8, Kd: 21 nM
            99.05%
1V209          
TLR7
    99.52%
CU-CPT17e
TLR3
TLR8
TLR9
          98.02%
Sparstolonin B      
TLR2
TLR4
      >99.0%
Isofraxidin        
TLR4
      98.14%
LHC-165          
TLR7
    98.17%
GSK2245035          
TLR7
    99.79%
Polygalasaponin F        
TLR4
      >99.0%
FSL-1 TFA      
TLR2
     
TLR6
99.58%
MMG-11      
TLR2
       
Okanin        
TLR4
      >98.0%
Enpatoran  
TLR8, IC50: 24.1 nM (in HEK293 cells)
TLR8, IC50: 620 nM (in peripheral blood mononuclear cells (PBMCs))
TLR8, IC50: 120 nM ( in whole blood (WB) cells)
     
TLR7, IC50: 11.1 nM (in HEK293 cells)
TLR7, IC50: 68.3 nM (in peripheral blood mononuclear cells (PBMCs))
TLR7, IC50: 2.2 nM ( in whole blood (WB) cells)
   
CU-115  
TLR8, IC50: 1.04 μM
     
TLR7, IC50: 50 μM
   
Robinin      
TLR2
TLR4
     
Imiquimod maleate          
TLR7