2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N13966
    Pyralomicin 2a
    Pyralomicin 2a is an antibiotic with antibacterial activity.
    Pyralomicin 2a
  • HY-W040271
    N-3-Hydroxydecanoyl-DL-homoserine lactone
    N-3-Hydroxydecanoyl-DL-Homoserine lactone is a bacterial quorum-sensing molecule. N-3-Hydroxydecanoyl-DL-Homoserine lactone activates the transcription factor SdiA (EC50 = 0.6 µM), which detects N-acyl homoserine lactones (AHLs), and exerts its effect in Salmonella enterica (S. enterica)12.
    N-3-Hydroxydecanoyl-DL-homoserine lactone
  • HY-N14252
    Melithiazole N
    Melithiazol N is an antibiotic. Melithiazole N is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity.
    Melithiazole N
  • HY-N14046
    Celesticetin B
    Celesticetin B is an antibiotic. Celesticetin B is mainly antibacterial against Gram-positive microorganisms.
    Celesticetin B
  • HY-N14310
    Hongoquercin A
    Hongoquercin A is a sesquiterpene antibiotic. Hongoquercin A has moderate anti-Gram-positive bacteria activity with a MIC of 4-8 μg/mL.
    Hongoquercin A
  • HY-117963
    Lincosamine
    Lincosamine is a lincosamide antibiotic with activity that inhibits bacterial growth. Lincosamine is primarily produced by Streptomyces lincolnensis. Lincosamine has shown efficacy in combating certain bacterial infections, especially against Klebsiella pneumoniae. Lincosamine ranked among 14 other antimicrobial compounds in its activity against Klebsiella pneumoniae in a test.
    Lincosamine
  • HY-B0506R
    Nadifloxacin (Standard)
    Nadifloxacin (Standard) is the analytical standard of Nadifloxacin (HY-B0506). This product is intended for research and analytical applications. Nadifloxacin (OPC7251) is a broad-spectrum quinolone antibiotic. Nadifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, interfering with DNA replication. It also suppresses the production of proinflammatory cytokines (such as IL-1α, IL-6, and IL-8). Nadifloxacin exhibits antibacterial activity against various pathogens, including Propionibacterium acnes and Staphylococcus aureus. Nadifloxacin also exhibits anti-inflammatory activity. Nadifloxacin can be used in the research of skin infections such as acne vulgaris, folliculitis, and impetigo.
    Nadifloxacin (Standard)
  • HY-B0506S1
    Nadifloxacin-d5
    Nadifloxacin-d5 (OPC7251-d5) is deuterium labeled Nadifloxacin (HY-B0506). Nadifloxacin (OPC7251) is a broad-spectrum quinolone antibiotic. Nadifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, interfering with DNA replication. It also suppresses the production of proinflammatory cytokines (such as IL-1α, IL-6, and IL-8). Nadifloxacin exhibits antibacterial activity against various pathogens, including Propionibacterium acnes and Staphylococcus aureus. Nadifloxacin also exhibits anti-inflammatory activity. Nadifloxacin can be used in the research of skin infections such as acne vulgaris, folliculitis, and impetigo.
    Nadifloxacin-d<sub>5</sub>
  • HY-N14905
    α-Prumycin hydrochloride
    α-Prumycin hydrochloride is a carbohydrate antibiotic. α-Prumycin hydrochloride has anti-fungal activity and weak anti-individual bacterial activity.
    α-Prumycin hydrochloride
  • HY-B0576R
    Sulfacetamide sodium (Standard)
    Sulfacetamide (Standard) (Sulphacetamide (Standard)) sodium is the analytical standard of Sulfacetamide sodium (HY-B0576). This product is intended for research and analytical applications. Sulfacetamide sodium is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium has antifungal and antibacterial activities.
    Sulfacetamide sodium (Standard)
  • HY-N14910
    Actiketal
    Actiketal is a glutarimide antibiotic that inhibits the incorporation of [3H]thymidine into EGF-stimulated Balb/MK cells.
    Actiketal
  • HY-N5186
    Cypemycin
    Cypemycin is a linaridin antibiotic that can inhibit cancer cell activity, inhibits P388 leukemia cells with IC50 of 1.3 μg/mL. Cypemycin can inhibit human tumor cells such as HeLa S3, HHCC-1, HCCS-M and Slex with IC50 of >25 μg/mL.
    Cypemycin
  • HY-N3012
    Isovalerylshikonin
    Isovalerylshikonin (IVS) is a shikonin pigment is identified in the root epidermis of Echium italicum L.
    Isovalerylshikonin
  • HY-N14294
    Fluvirucin A1
    Fluvirucin A1 is an antibiotic against influenza A virus.
    Fluvirucin A1
  • HY-N14081
    Monamycin G3
    Monamycin G3 is an ester peptide antibiotic. Monamycin G3 has activity against Gram-positive bacteria.
    Monamycin G3
  • HY-112586R
    Sulfaethoxypyridazine (Standard)
    Sulfaethoxypyridazine (Standard) is the analytical standard of Sulfaethoxypyridazine. This product is intended for research and analytical applications. Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs.
    Sulfaethoxypyridazine (Standard)
  • HY-Y1826R
    IITR01324 (Standard)
    IITR01324 (Standard) is the analytical standard of IITR01324. This product is intended for research and analytical applications. IITR01324 is an antimicrobial agent. IITR01324 has antimicrobial activity against Escherichia coli (MIC=3.58 mg/L) and other Gram-negative bacteria (Shigella flexneri: MIC=3.58 mg/L; Cronobacter sakazakii: MIC=28.63 mg/L). IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases. IITR01324 can be used to study the development of new antimicrobial drugs, especially against multidrug-resistant (MDR) pathogens.
    IITR01324 (Standard)
  • HY-14957R
    Ozenoxacin (Standard)
    Ozenoxacin (Standard) is the analytical standard of Ozenoxacin. This product is intended for research and analytical applications. Ozenoxacin is a nonfluorinated quinolone antibacterial, which shows potent activities against the main microorganisms isolated from skin and soft tissue infections.
    Ozenoxacin (Standard)
  • HY-13062R
    Daunorubicin hydrochloride (Standard)
    Daunorubicin (hydrochloride) (Standard) is the analytical standard of Daunorubicin (hydrochloride). This product is intended for research and analytical applications. Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor.
    Daunorubicin hydrochloride (Standard)
  • HY-W705651
    Econazole nitrate-d6
    Econazole nitrate-d6 is deuterium labeled Econazole (nitrate). Econazole nitrate is an imidazole class antifungal medication. Econazole nitrate also has antibacterial activity.
    Econazole nitrate-d<sub>6</sub>
Antibiotic Isoform Comparison

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