1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W706112
    Chloramphenicol-d5-2
    Chloramphenicol-d5-2 is the deuterium labeled Chloramphenicol (HY-B0239). Chloramphenicol is an orally active, potent and broad-spectrum antibiotic.
    Chloramphenicol-d<sub>5</sub>-2
  • HY-N14682
    Helvolinic acid
    HHelvolinic acid is a steroidal antibiotic. Helvolinic acid has anti-Gram-positive bacterial activity.
    Helvolinic acid
  • HY-N14371
    Menoxymycin B
    Menoxymycin B is an antibiotic. Menoxymycin B has a cytotoxic effect. Menoxymycin B inhibits KB and N18-RE-105 cells with IC50s of 0.22 μM and 0.023 μM.
    Menoxymycin B
  • HY-B1043R
    Piromidic acid (Standard)
    Piromidic acid (Standard) is the analytical standard of Piromidic acid. This product is intended for research and analytical applications. Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci and can be used for the research of intestinal, urinary, and biliary tract infections.
    Piromidic acid (Standard)
  • HY-N15179
    Minosaminomycin
    Minosaminomycin is an antibiotic containing myo-inosamine that can be extracted from Streptomyces No. MA514A1. Minosaminomycin exerts antimicrobial activity against Mycobacterium smegrnatis ATCC 607 and Mycobacterium phlei (MIC= 1.56/6.25 mcg/mL).
    Minosaminomycin
  • HY-101575
    Acetylazide
    Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
    Acetylazide
  • HY-101739
    Amcinafal
    Amcinafal is an active diol, used against virus replication and interferon production.
    Amcinafal
  • HY-101818
    PNU288034
    PNU288034 is a potent oxazolidinone antibiotic.
    PNU288034
  • HY-B0579S1
    Cyclosporin A-d3
    Cyclosporin A-d3 (Cyclosporine A-d3) is the deuterated-labeled Cyclosporin A (HY-B0579). Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM. Cyclosporin A is a molecular glue, binds to cyclophilin and calcineurin, leading to inactivation of nuclear Factor of activated T Cells (NFAT) and a subsequent decrease in the immune response. Cyclosporin A also inhibits CD11a/CD18 adhesion.
    Cyclosporin A-d<sub>3</sub>
  • HY-113945
    Abbeymycin
    Abbeymycin is an antibiotic derived from the actinobacterium Streptomyces sp. AB-999F-52. Abbeymycin is a specifically acting antibiotic with antimicrobial activity, primarily targeting anaerobic bacteria. Abbeymycin is employed in research concerning antibiotic discovery and screening.
    Abbeymycin
  • HY-N13983
    Arylomycin B4
    Arylomycin B4 is a lipohexapeptide antibiotic against Gram-positive bacteria.
    Arylomycin B4
  • HY-108913R
    Nitrocefin (Standard)
    Nitrocefin (Standard) is the analytical standard of Nitrocefin. This product is intended for research and analytical applications. Nitrocefin is a chromogenic β-lactamase substrate that undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics.
    Nitrocefin (Standard)
  • HY-117818
    Sapurimycin
    Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA.
    Sapurimycin
  • HY-B1358R
    Lincomycin hydrochloride monohydrate (Standard)
    Lincomycin (U-10149) hydrochloride monohydrate (Standard) is the analytical standard of Lincomycin hydrochloride monohydrate (HY-B1358). This product is intended for research and analytical applications. Lincomycin hydrochloride monohydrate is an orally active lincosamide antibiotic. Lincomycin hydrochloride monohydrate binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride monohydrate can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride monohydrate induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.
    Lincomycin hydrochloride monohydrate (Standard)
  • HY-N14011
    Cedarmycin A
    Cedarmycin A has activities against Candida, Cryptococcus neoforme and Aspergillus fumigatus, with the MIC values of 12.5-50 μg/mL.
    Cedarmycin A
  • HY-N14726
    Primocarcin
    Primocarcin is an antibiotic that inhibits Ehrlich ascites cancer.
    Primocarcin
  • HY-17425AS1
    Valacyclovir-d4 hydrochloride
    Valacyclovir-d4 (hydrochloride) is the deuterium labeled Valacyclovir hydrochloride. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422).
    Valacyclovir-d<sub>4</sub> hydrochloride
  • HY-180328
    3''-Deamino-3''-hydroxykanamycin B
    3''-Deamino-3''-hydroxykanamycin B (NK-1012-1) is a kanamycin antibiotic. 3''-Deamino-3''-hydroxykanamycin B can be produced by S. tenebrarius. 3''-Deamino-3''-hydroxykanamycin B is effective against E. coli ATCC 25922 and E. coli CCARM 1A020, with MIC values of 128 μg/mL.
    3''-Deamino-3''-hydroxykanamycin B
  • HY-N14282
    Ezomycin B2
    Ezomycin B2 is an antibiotic with antifungal activity.
    Ezomycin B2
  • HY-117183
    Lankacidinol
    Lankacidinol (T-2636 F) is an antibiotic. Lankacidinol and its related metabolites 2,18-seco-lankacidinol A (1) and 2,18-seco-lankacidinol B (2) have significant biological activities and potential medicinal value. In addition, 2,18-seco-lankacidinol A exhibits potent antitumor activity.
    Lankacidinol

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