2. Signaling Pathways
  3. Others
  4. Drug Isomer

Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (432):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W674436
    (S)-Thalidomide-4-OH
    		98.0%
    (S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
    (S)-Thalidomide-4-OH
  • HY-112319
    (R,S)-MK-8457
    (R,S)-MK-8457 is a stereoisomer of MK-8457. MK-8457 is a dual inhibitor of Syk and ZAP70.
    (R,S)-MK-8457
  • HY-W698462
    (S)-3-Hydroxymyristic acid
    		99.73%
    (S)-3-Hydroxymyristic acid ((3S)-3-Hydroxytetradecanoic acid) is the enantiomer of (R)-3-hydroxytetradecanoic acid (a lipid A component) (HY-W288375), and enhances the inherent immune adjuvant activity of lipid A.
    (S)-3-Hydroxymyristic acid
  • HY-106266C
    (R)-Chiglitazar
    (R)-Chiglitazar is the enantiomer of Chiglitazar (HY-106266). Chiglitazar is a peroxisome PPAR agonist that can be used for the study of type 2 diabetes.
    (R)-Chiglitazar
  • HY-153193A
    (1R)-LSN3160440
    		98.43%
    (1R)-LSN3160440 is the (1R) chiral isomer of LSN3160440 (HY-153193). LSN3160440 is an allosteric modulator of GLP-1R.
    (1R)-LSN3160440
  • HY-14190A
    (rac)-Valategrast
    (rac)-Valategrast ((rac)-R-411 free base) is a racemic compound of Valategrast (HY-14190). Valategrast is a potent, orally active dual antagonist of integrin α4β1 (VLA-4) and α4β7. Valategrast may be used in research on chronic obstructive pulmonary disease (COPD) and asthma.
    (rac)-Valategrast
  • HY-165135
    Rac-Sphingosylphosphorylcholine
    		98%
    Rac-Sphingosylphosphorylcholine is a racemate of Sphingosylphosphorylcholine (HY-132187).
    Rac-Sphingosylphosphorylcholine
  • HY-B0823A
    (E/Z)-Acetamiprid
    (E/Z)-Acetamiprid is the E/Z mixture of Acetamiprid (HY-B0823). Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders.
    (E/Z)-Acetamiprid
  • HY-148124
    6-epi Doxycycline
    		98.47%
    6-Epi-doxycycline is the C-6 epimer of Doxycycline (HY-N0565), formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity). 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations.
    6-epi Doxycycline
  • HY-176710A
    (R)-PAD-PF2
    		99.95%
    (R)-PAD-PF2 is an isomer of PAD-PF2 (HY-176710). PAD-PF2 is a PAD family inhibitor, as well as a κ-opioid receptor agonist (EC50 = 7.55 μM) and an M1 muscarinic acetylcholine receptor antagonist (IC50 = 12.3 μM).
    (R)-PAD-PF2
  • HY-W073501
    trans-Glutaconic acid
    		98.92%
    trans-Glutaconic acid (trans-2-Pentenedioic acid) is the trans isomer of Glutaconic acid (HY-W073501A). trans-Glutaconic acid is a neurotoxic metabolite. trans-Glutaconic acid induces weak neurotoxicity in cultured cerebral neocortical neurons. trans-Glutaconic acid elicits significant electrophysiological responses in rat neocortical wedge preparations at high concentrations. trans-Glutaconic acid can be used in studies related to glutaric acidemia type 1.
    trans-Glutaconic acid
  • HY-100218CR
    (1R,3R)-RSL3 (Standard)
    		Control
    (1R,3R)-RSL3 (Standard) is the analytical standard of (1R,3R)-RSL3 (HY-100218C). This product is intended for research and analytical applications. (1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.
    (1R,3R)-RSL3 (Standard)
  • HY-141411B
    (R)-Zevaquenabant
    		99.15%
    (R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant (HY-141411A). Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual cannabinoid CB1 receptor and inducible NOS antagonist. Zevaquenabant ameliorates obesity-induced chronic kidney disease (CKD).
    (R)-Zevaquenabant
  • HY-153275A
    KM-001-E2
    		99.08%
    (S)-KM-001 ((S)-KM-001) is the enantiomer of KM-001 (HY-153275). KM-001 is a TRPV3 channel antagonist and can be used for studying skin itching and keratinosis diseases.
    KM-001-E2
  • HY-172009
    8-Amino-7-oxononanoic acid hydrochloride
    8-Amino-7-oxononanoic acid hydrochloride is a racemic mixture of 8(R)-KAPA and the vitamer of biotin 8(S)-KAPA.
    8-Amino-7-oxononanoic acid hydrochloride
  • HY-112382
    Iso-Olomoucine
    		99.90%
    Iso-olomoucine is an inactive stereoisomer of the CDK5 inhibitor olomoucine with IC50 >1 mM.
    Iso-Olomoucine
  • HY-18299B
    (S)-Purvalanol B
    		98.0%
    (S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor.
    (S)-Purvalanol B
  • HY-N15910
    ent-DMPC
    ent-DMPC is an enantiomer of Colfosceril miristate (DMPC) (HY-109541).
    ent-DMPC
  • HY-148336
    (E)-IDO1/TDO-IN-5
    (E)-IDO1/TDO-IN-5 is the E configuration of IDO1/TDO-IN-5 (HY-148336A). IDO1/TDO-IN-5 is a dual IDO1/TDO inhibitor with IC50 values of 0.018 and 0.025 μM, respectively.
    (E)-IDO1/TDO-IN-5
  • HY-W012732R
    Isoquinoline (Standard)
    Isoquinoline (Standard) is the analytical standard of Isoquinoline. This product is intended for research and analytical applications. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities.
    Isoquinoline (Standard)