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Cat. No.: HY-153275A

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KM-001-E2

Name: KM-001-E2
Brand: MedChemExpress
SKU: HY-153275A
Price: 760.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (S)-KM-001)

고객리뷰

Based on 1 Customer Validation

(S)-KM-001 ((S)-KM-001) is the enantiomer of KM-001 (HY-153275). KM-001 is a TRPV3 channel antagonist and can be used for studying skin itching and keratinosis diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 99.08%
CAS No.: 2682864-43-1
화학식: C₂₆H₂₅FN₂O₂
분자량:416.49

보관:

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

KM-001-E2 Chemical Structure

CAS No.: 2682864-43-1

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

(S)-KM-001 ((S)-KM-001) is the enantiomer of KM-001 (HY-153275). KM-001 is a TRPV3 channel antagonist and can be used for studying skin itching and keratinosis diseases^[1].

Chemical Information

CAS No. 2682864-43-1
Appearance Solid
분자량 416.49
화학식 C₂₆H₂₅FN₂O₂
Color White to off-white
SMILES

OCC1=C([C@H]2CN(CC2)C(C3=CC=C(C=N3)F)=O)C=CC(C4=C(C5CC5)C=CC=C4)=C1
Synonyms

(S)-KM-001
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Barak SL, et al. 629 Evaluating the safety and efficacy of topical KM-001, a TRPV3 inhibitor, for treatment of pruritus in patients with Lichen Simplex Chronicus (LSC): a first in human, double-blind, randomized vehicle-controlled study. Journal of Investigative Dermatology. 2023 May 1;143(5):S108.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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