2. Others Protein Tyrosine Kinase/RTK
  3. Drug Isomer Syk
  4. (R,S)-MK-8457

(R,S)-MK-8457 is a stereoisomer of MK-8457. MK-8457 is a dual inhibitor of Syk and ZAP70.

For research use only. We do not sell to patients.

(R,S)-MK-8457

(R,S)-MK-8457 Chemical Structure

CAS No. : 1312518-84-5

Size Price Stock Quantity
5 mg Get quote 16 - 18 weeks 15 - 17 weeks 17 - 19 weeks 15 - 17 weeks
10 mg Get quote 16 - 18 weeks 15 - 17 weeks 17 - 19 weeks 15 - 17 weeks
25 mg Get quote 16 - 18 weeks 15 - 17 weeks 17 - 19 weeks 15 - 17 weeks
50 mg Get quote 16 - 18 weeks 15 - 17 weeks 17 - 19 weeks 15 - 17 weeks
100 mg   Get quote  
200 mg   Get quote  
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Other Forms of (R,S)-MK-8457:

(R,S)-MK-8457 Related Antibodies

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Description

(R,S)-MK-8457 is a stereoisomer of MK-8457. MK-8457 is a dual inhibitor of Syk and ZAP70[1].

In Vitro

MK-8457 is primarily used in research on rheumatoid arthritis, and its application in hypertension has also been investigated[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(R,S)-MK-8457 Related Antibodies
Clinical Trial
Molecular Weight

506.54

Formula

C24H25F3N4O3S
CAS No.
SMILES

O=C([C@@H]1C(C)(C)C[C@](C2=NC=C(C3=CC(NC4=NC=CC(C(F)(F)F)=N4)=CC(C)=C3)S2)(O)CC1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(R,S)-MK-8457 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R,S)-MK-84571312518-84-5Drug IsomerSykSpleen tyrosine kinasedrug metabolismstructure-activity relationship studiesspleen tyrosine kinasepharmacokinetic studiesInhibitorinhibitorinhibit

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