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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-47176
    QTZ
    QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core.
    QTZ
  • HY-D1570
    BODIPY FL C12
    		99.79%
    BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 480/508 nm.
    BODIPY FL C12
  • HY-162160
    NR12S
    		98.75%
    NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes.
    NR12S
  • HY-W011009
    PTCDA
    		≥98.0%
    PTCDA is an organic dye molecule and an organic semiconductor.
    PTCDA
  • HY-131028
    Janelia Fluor® 646 TFA
    Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 646 TFA
  • HY-P4326
    Boc-Val-Pro-Arg-AMC
    		99.26%
    Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity.
    Boc-Val-Pro-Arg-AMC
  • HY-D2096
    Alexa fluor 647 NHS ester
    Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    Alexa fluor 647 NHS ester
  • HY-D1685
    BZiPAR
    BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease.
    BZiPAR
  • HY-D1613
    BODIPY FL C5-HPC
    		99.43%
    BODIPY FL C5-HPC is a lipophilic green fluorescent dye (Ex/Em: 500/510 nm).
    BODIPY FL C5-HPC
  • HY-NP0182
    Peanut Agglutinin (Biotinylated)
    Peanut Agglutinin (PNA) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Biotinylated is a biological material or organic compound that can be used in life science research.
    Peanut Agglutinin (Biotinylated)
  • HY-DY1008
    Nile Red (solution)
    Nile Red (solution) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm.
    Solvent and concentration: DMSO: 1 mM
    Nile Red (solution)
  • HY-W103047
    1-Pyrenebutyric acid
    		98.89%
    1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells.
    1-Pyrenebutyric acid
  • HY-DY1074
    ER-Tracker Blue-White DPX (solution)
    ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Staining followed by fixation is possible, but cells fixed with aldehydes will only retain partial fluorescence.
    Solvent and concentration: DMSO: 1 mM
    ER-Tracker Blue-White DPX (solution)
  • HY-P4154
    Bevonescein
    		Inhibitor 99.11%
    Bevonescein (ALM-488) is a fluorescein-conjugated peptide that facilitates the targeted delivery of a fluorescent moiety (5-FAM (HY-66022)) to nerves after intravenous (IV) administration. Bevonescein binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves (Ex/Em = 480/530 nm).
    Bevonescein
  • HY-D0824
    CY7-SE
    		≥98.0%
    CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    CY7-SE
  • HY-D0933
    Auramine O
    Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria.
    Auramine O
  • HY-145519
    Mu-6S-Palm-β-Glc
    		99.9%
    Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants.
    Mu-6S-Palm-β-Glc
  • HY-D1703
    Oxazine 170 perchlorate
    		98.81%
    Oxazine 170 perchlorate is a laser dye with a wide excitation spectrum range (300−550 nm), which strongly absorbs light with a wavelength greater than 550 nm, and it emits fluorescence with a wavelength of about 645 nm.
    Oxazine 170 perchlorate
  • HY-D0075
    DHPDS disodium salt
    		98.61%
    DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver.
    DHPDS disodium salt
  • HY-114289
    6-HEX
    		98.89%
    6-HEX is one kind of light base group, the wave length is 532 nm, the wave length is 556 nm. 6-HEX can be used to record nucleic acid sequences and design optical materials. 6-HEX can be used to record nucleic acids at 543 nm radiation, and at 550 nm and 650 nm radiation (5 nm radiation), it can be used to directly locate the base of the cell group.
    6-HEX
Cat. No. Product Name / Synonyms Application Reactivity