1-Pyrenebutyric acid
Based on 1 Customer Validation
1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells.
For research use only. We do not sell to patients.
- Purity: 98.89%
- CAS No.: 3443-45-6
- Formula: C20H16O2
- Molecular Weight:288.35
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 3443-45-6
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Appearance Solid
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Molecular Weight 288.35
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Formula C20H16O2
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Color Light yellow to light brown
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SMILES
C1=CC2=C3C(=C1)C=CC4=C(CCCC(=O)O)C=CC(=C43)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (346.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang L, et, al. Fluorescence determination of DNA with 1-pyrenebutyric acid nanoparticles coated with beta-cyclodextrin as a fluorescence probe. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Apr;61(6):1201-5. [Content Brief]
[2]. Hinnemo M, et, al. On Monolayer Formation of Pyrenebutyric Acid on Graphene. Langmuir. 2017 Apr 18;33(15):3588-3593. [Content Brief]
[3]. Rharass, T., et al., (2006). Variation of 1-pyrenebutyric acid fluorescence lifetime in single living cells treated with molecules increasing or decreasing reactive oxygen species levels. Analytical biochemistry, 357(1), 1–8. [Content Brief]
[4]. Moné, Y., et al., (2011). An example of molecular co-evolution: reactive oxygen species (ROS) and ROS scavenger levels in Schistosoma mansoni/Biomphalaria glabrata interactions. International journal for parasitology, 41(7), 721–730. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4680 mL | 17.3400 mL | 34.6801 mL | 86.7002 mL |
| 5 mM | 0.6936 mL | 3.4680 mL | 6.9360 mL | 17.3400 mL | |
| 10 mM | 0.3468 mL | 1.7340 mL | 3.4680 mL | 8.6700 mL | |
| 15 mM | 0.2312 mL | 1.1560 mL | 2.3120 mL | 5.7800 mL | |
| 20 mM | 0.1734 mL | 0.8670 mL | 1.7340 mL | 4.3350 mL | |
| 25 mM | 0.1387 mL | 0.6936 mL | 1.3872 mL | 3.4680 mL | |
| 30 mM | 0.1156 mL | 0.5780 mL | 1.1560 mL | 2.8900 mL | |
| 40 mM | 0.0867 mL | 0.4335 mL | 0.8670 mL | 2.1675 mL | |
| 50 mM | 0.0694 mL | 0.3468 mL | 0.6936 mL | 1.7340 mL | |
| 60 mM | 0.0578 mL | 0.2890 mL | 0.5780 mL | 1.4450 mL | |
| 80 mM | 0.0434 mL | 0.2168 mL | 0.4335 mL | 1.0838 mL | |
| 100 mM | 0.0347 mL | 0.1734 mL | 0.3468 mL | 0.8670 mL |
1-Pyrenebutyric acid Related Classifications
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