1-Pyrenebutyric acid

Cat. No.: HY-W103047 Purity: 98.89%: Data Sheet
COA

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Handling Instructions
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1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells.

For research use only. We do not sell to patients.

1-Pyrenebutyric acid Chemical Structure

CAS No. : 3443-45-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

288.35

Formula

C₂₀H₁₆O₂

CAS No.

3443-45-6

Appearance

Solid

Color

Light yellow to light brown

SMILES

C1=CC2=C3C(=C1)C=CC4=C(CCCC(=O)O)C=CC(=C43)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (346.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4680 mL	17.3400 mL	34.6801 mL
5 mM	0.6936 mL	3.4680 mL	6.9360 mL
10 mM	0.3468 mL	1.7340 mL	3.4680 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.89%

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Data Sheet (274 KB) SDS (393 KB)

COA (250 KB) HNMR (125 KB) RP-HPLC (234 KB)

Handling Instructions (2659 KB)

References

[1]. Wang L, et, al. Fluorescence determination of DNA with 1-pyrenebutyric acid nanoparticles coated with beta-cyclodextrin as a fluorescence probe. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Apr;61(6):1201-5. [Content Brief]

[2]. Hinnemo M, et, al. On Monolayer Formation of Pyrenebutyric Acid on Graphene. Langmuir. 2017 Apr 18;33(15):3588-3593. [Content Brief]

[3]. Rharass, T., et al., (2006). Variation of 1-pyrenebutyric acid fluorescence lifetime in single living cells treated with molecules increasing or decreasing reactive oxygen species levels. Analytical biochemistry, 357(1), 1–8. [Content Brief]

[4]. Moné, Y., et al., (2011). An example of molecular co-evolution: reactive oxygen species (ROS) and ROS scavenger levels in Schistosoma mansoni/Biomphalaria glabrata interactions. International journal for parasitology, 41(7), 721–730. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4680 mL	17.3400 mL	34.6801 mL	86.7002 mL
	5 mM	0.6936 mL	3.4680 mL	6.9360 mL	17.3400 mL
	10 mM	0.3468 mL	1.7340 mL	3.4680 mL	8.6700 mL
	15 mM	0.2312 mL	1.1560 mL	2.3120 mL	5.7800 mL
	20 mM	0.1734 mL	0.8670 mL	1.7340 mL	4.3350 mL
	25 mM	0.1387 mL	0.6936 mL	1.3872 mL	3.4680 mL
	30 mM	0.1156 mL	0.5780 mL	1.1560 mL	2.8900 mL
	40 mM	0.0867 mL	0.4335 mL	0.8670 mL	2.1675 mL
	50 mM	0.0694 mL	0.3468 mL	0.6936 mL	1.7340 mL
	60 mM	0.0578 mL	0.2890 mL	0.5780 mL	1.4450 mL
	80 mM	0.0434 mL	0.2168 mL	0.4335 mL	1.0838 mL
	100 mM	0.0347 mL	0.1734 mL	0.3468 mL	0.8670 mL