Peanut Agglutinin (Biotinylated)

Peanut Agglutinin Biotinylated (4 µg; 30 min) specifically binds to sperm equatorial segment protein 1 as its primary glycoprotein target in wild-type mouse testis lysate, with SPESP1 detected in all six purification and LC-MS/MS analyses^[1].
Peanut Agglutinin Biotinylated (10 μM/mL; 30 minutes plus 30 minutes with mouse liver powder) selectively stains histiocytosis X cells and interdigitating reticulum cells with a unique surface and paranuclear pattern, distinguishes these cells from benign macrophage-histiocytes via staining pattern differences, and fails to produce a signal in malignant histiocytosis and monoblastic leukemia cells, enabling differential diagnosis in paraffin-embedded human tissues^[3].
Biotinylated Peanut Agglutinin (Biotinylated) (5 µg/mL; 1 h) detects significantly elevated circulating TF-antigen (mean absorbance 0.319-0.411) in pre- and post-treatment well, moderately, and poorly differentiated human esophageal squamous cell carcinoma patients, with an overall sensitivity of 87.5% and specificity of 90%^[4].
Peanut Agglutinin Biotinylated detects TF-antigen expression in all human esophageal squamous cell carcinoma specimens, with intense expression present in 52.0% of moderately differentiated and 54.55% of poorly differentiated ESCC specimens, compared to only 8.70% of well differentiated ESCC specimens^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.