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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10875):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W705168
    Yangonin-d3
    Yangonin-d3 is the deuterium labeled Yangonin (HY-N0919). Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC50 and a Ki of 1.79 μM and 0.72 μM, respectively.
    Yangonin-d<sub>3</sub>
  • HY-A0114S
    Moexiprilat-d5
    Moexiprilat-d5 is deuterium labeled Moexiprilat.
    Moexiprilat-d<sub>5</sub>
  • HY-W751156
    O-Phospho-L-serine-13C3
    O-Phospho-L-serine-13C3 (L-Serine O-phosphate-13C3) is the 13C-labeled O-Phospho-L-serine (HY-15129). O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2.
    O-Phospho-L-serine-<sup>13</sup>C<sub>3</sub>
  • HY-181631S
    4-[[[(2-((tert-Butoxycarbonyl)amino)ethyl)amino]carbonyl]methyl]-7-hydroxy-2H-chromen-2-one-d9
    4-[[[(2-((tert-Butoxycarbonyl)amino)ethyl)amino]carbonyl]methyl]-7-hydroxy-2H-chromen-2-one-d9 is the deuterium labeled 4-[[[(2-((tert-Butoxycarbonyl)amino)ethyl)amino]carbonyl]methyl]-7-hydroxy-2H-chromen-2-one.
    4-[[[(2-((tert-Butoxycarbonyl)amino)ethyl)amino]carbonyl]methyl]-7-hydroxy-2H-chromen-2-one-d<sub>9</sub>
  • HY-W013812S3
    Ethyl linoleate-d11
    Ethyl linoleate-d11 (Linoleic Acid ethyl ester-d11) is deuterium labeled Ethyl linoleate. Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators.
    Ethyl linoleate-d<sub>11</sub>
  • HY-143790S
    N-2-(Hydroxyethyl)-L-valine-d4
    N-2-(Hydroxyethyl)-L-valine-d4 is the deuterium labeled N-2-(Hydroxyethyl)-L-valine.
    N-2-(Hydroxyethyl)-L-valine-d<sub>4</sub>
  • HY-15037S
    Diclofenac-13C6 sodium heminonahydrate
    Diclofenac-13C6 (sodium heminonahydrate) is the 13C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
    Diclofenac-<sup>13</sup>C<sub>6</sub> sodium heminonahydrate
  • HY-10053S
    Maropitant-d3
    Maropitant-d3 is the deuterium labeled Maropitant. Maropitant is a selective and orally active neurokinin (NK1) receptor antagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ). Maropitant is highly effective in preventing vomiting.
    Maropitant-d<sub>3</sub>
  • HY-W007928S
    1-O-Acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranoside-13C
    1-O-Acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranoside-13C is the 13C labeled D-Ribulose.
    1-O-Acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranoside-<sup>13</sup>C
  • HY-W005355S
    Sodium 2-oxobutanoate-13C4,d2 hydrate
    Sodium 2-oxobutanoate-13C4,d2 (hydrate) is the deuterium and 13C labeled Sodium 2-oxobutanoate hydrate.
    Sodium 2-oxobutanoate-<sup>13</sup>C<sub>4</sub>,d<sub>2</sub> hydrate
  • HY-W703174
    Methyl-d3 hydrazinecarboxylate
    Methyl-d3 hydrazinecarboxylate is the deuterium labeled Methyl hydrazinecarboxylate (HY-Y0902).
    Methyl-d<sub>3</sub> hydrazinecarboxylate
  • HY-154775S
    Ethinylestradiol sulfate-d4
    Ethinylestradiol sulfate-d4 is deuterated labeled Ethinylestradiol sulfate.
    Ethinylestradiol sulfate-d<sub>4</sub>
  • HY-Y0747S1
    Iodobenzene-d2
    Iodobenzene-d2 is the deuterium labeled 1-Iodobenzene. Iodobenzene can undergo Ullmann coupling reaction on copper catalyst to generate biphenyl. Iodobenzene can undergo Suzuki reaction with phenylboronic acid to generate biphenyl.
    Iodobenzene-d<sub>2</sub>
  • HY-W765751
    trans-3'-Hydroxy Cotinine-d3 N-b-D-Glucuronide
    trans-3'-Hydroxy Cotinine-d3 N-b-D-Glucuronide is the deuterium labeled trans-3'-Hydroxy Cotinine N-b-D-Glucuronide.
    trans-3'-Hydroxy Cotinine-d<sub>3</sub> N-b-D-Glucuronide
  • HY-142440S
    Apatinib 25-N-oxide-d8 dihydrochloride
    Apatinib 25-N-oxide-d8 (dihydrochloride) is the deuterium labeled Apatinib 25-N-oxide dihydrochloride.
    Apatinib 25-N-oxide-d<sub>8</sub> dihydrochloride
  • HY-N2041S5
    Myristic acid-d1
    Myristic acid-d is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
    Myristic acid-d<sub>1</sub>
  • HY-Y1352S1
    Potassium cyanate-13C,15N
    Potassium cyanate-13C,15N is the 13C and 15N labeled Potassium cyanate.
    Potassium cyanate-<sup>13</sup>C,<sup>15</sup>N
  • HY-132184S
    5,6-Epoxyeicosatrienoic acid-d11
    5,6-Epoxyeicosatrienoic acid-d11 (5,6-EET-d11) is deuterium labeled 5,6-Epoxyeicosatrienoic acid. 5,6-Epoxyeicosatrienoic acid is one of the four major epoxyeicosatrienoic acid (EET) isomers metabolized from Arachidonic acid (HY-109590). 5,6-Epoxyeicosatrienoic acid induces peripheral vasodilation and lowers blood pressure by inhibiting T-type calcium channels (Cav3.2: IC50 = 0.54 μM). 5,6-Epoxyeicosatrienoic acid causes vasoconstriction in hypoxic pulmonary blood vessels via activating Rho kinase in a membrane depolarization-dependent manner. 5,6-Epoxyeicosatrienoic acid induces mechanical pain by activating TRPA1. 5,6-Epoxyeicosatrienoic acid can be used in studies related to hypoxic pulmonary vasoconstriction, mechanical hyperalgesia and hypertension.
    5,6-Epoxyeicosatrienoic acid-d<sub>11</sub>
  • HY-166904S
    2,2′,4,4′,6-Pentabromo diphenyl ether-13C12
    2,2′,4,4′,6-Pentabromo diphenyl ether-13C12 is 13C labeled 2,2′,4,4′,6-Pentabromo diphenyl ether.
    2,2′,4,4′,6-Pentabromo diphenyl ether-<sup>13</sup>C<sub>12</sub>
  • HY-142255S1
    Saroglitazar sulfoxide-d4
    Saroglitazar sulfoxide-d4 is the deuterium labeled Saroglitazar sulfoxide.
    Saroglitazar sulfoxide-d<sub>4</sub>