Adenine monohydrochloride hemihydrate

製品番号: HY-W015213 純度: 99.87%: Data Sheet SDS COA 取扱説明書
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Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号 : 6055-72-7

容量	価格（税別）	在庫状況	数量

>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solid
1 g	$25	在庫あり	Estimated Time of Arrival: December 31
5 g		お問い合わせ
10 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 22 publication(s) in Google Scholar

Other Forms of Adenine monohydrochloride hemihydrate:

Adenine 在庫あり
Adenine monohydrochloride hemihydrate-¹⁵N₅ お問い合わせ
Adenine monohydrochloride hemihydrate (Standard) お問い合わせ

顧客検証

In Vivo Efficacy Study

Bio/Physico-chemical Assay

IHC

: Adenine monohydrochloride hemihydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]; Capsaicin (10 and 15mg/kg, i.p.,once per week for 8 weeks) treatment lessened the deposition of ECM proteins in the kidneys from Adenine (0.25% w/w)-fed mice. Representative images of MTS (blue color), Picrosirius Red staining (red color), and IF staining of fibronectin (red color) and COL1A1 (green color) for kidney sections from adenine-fed (Adenine) or normal-fed (Ctrl) mice. Scale bars are 50 μm.

: Adenine monohydrochloride hemihydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]; Capsaicin (10 and 15 mg/kg, i.p., once per week for 8 weeks) treatment lessened the deposition of ECM proteins in the kidneys from Adenine (0.25% w/w)-fed mice. WB images of fibronectin and COL1A1 expressions in kidney lysates from mice.

: Adenine monohydrochloride hemihydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]; Capsaicin(10 or 15 mg/kg, i.p., once per week for 8 weeks) improved survival rate of Adenine (0.25% w/w)-fed mice. (A) Relative weight curves of indicated mice as described in A (n = 6). Mouse weight is measured once per 3 days, the initial weight is set to 1, and day 0 means the time point starting Adenine-rich diet. (B) Kaplan-Meier survival analysis of indicated mice as described in A (n = 12). Data are means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001.

: Adenine monohydrochloride hemihydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]; Capsaicin(10 or 15 mg/kg, i.p., once per week for 8 weeks) improved kidney function of Adenine (0.25% w/w)-fed mice. Concentrations of serum creatinine, urea, and albumin from mice (n = 8). Data are means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001.

: Adenine monohydrochloride hemihydrate purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]; Capsaicin(10 or 15 mg/kg, i.p., once per week for 8 weeks) treatment prevented phenotypic alteration of tubular epithelial cells in the kidneys from Adenine (ADE) (0.25% w/w)-fed mice. Representative IHC staining images of E-cadherin and vimentin kidney sections from mice. Scale bars are 25 μm.

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

分子量

189.60

分子式

C₅H₈ClN₅O

CAS 番号

6055-72-7

Appearance

Solid

Color

White to off-white

SMILES

NC(N=CN1)=C2C1=NC=N2.Cl.O

Structure Classification

Others

Initial Source

Endogenous metabolite

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶剤 & 溶解度

体外:

DMSO : 8.33 mg/mL (43.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.2743 mL	26.3713 mL	52.7426 mL
5 mM	1.0549 mL	5.2743 mL	10.5485 mL
10 mM	0.5274 mL	2.6371 mL	5.2743 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.87%

Select Batch:

データシート (304 KB) SDS (393 KB)

COA (252 KB) HNMR (244 KB) RP-HPLC (256 KB) MS (203 KB)

取扱説明書 (2659 KB)

参考文献

[1]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27. [Content Brief]

[2]. Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.

[3]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.2743 mL	26.3713 mL	52.7426 mL	131.8565 mL
	5 mM	1.0549 mL	5.2743 mL	10.5485 mL	26.3713 mL
	10 mM	0.5274 mL	2.6371 mL	5.2743 mL	13.1857 mL
	15 mM	0.3516 mL	1.7581 mL	3.5162 mL	8.7904 mL
	20 mM	0.2637 mL	1.3186 mL	2.6371 mL	6.5928 mL
	25 mM	0.2110 mL	1.0549 mL	2.1097 mL	5.2743 mL
	30 mM	0.1758 mL	0.8790 mL	1.7581 mL	4.3952 mL
	40 mM	0.1319 mL	0.6593 mL	1.3186 mL	3.2964 mL